Statistics & Publications

DFG Call for "Core Facilities and Networks 2015

The LIC was successful in the  DFG Call for "Core Facilities and Networks 2015" Freiburg has been awarded a grant over three years  for realization of the Microscopy and Image Analysis Platform Freiburg (MIAP-Freiburg).

MIAP-Freiburg will establish a series of interdisciplinary seminars and workshops covering in great depth special topics in microscopy and related fields. The activities, which are arranged as a cooperation of academia and industry, are targeted towards scientific users of microscopical techniques in the life and material sciences, computer scientists in the area of image analysis and software development, engineers and physicists from basic research, instrument developers in the whole area of microscopy and finally staff from imaging facilities world-wide.

Moreover the LIC application as an "Advanced Light Microscopy Multi Modal Single Sited Node" within EuroBioImaging was excellently reviewed by an independent International Evaluation Board and received the final ranking: Highly Recommended Expression of Interest for Euro-BioImaging Node.

The LIC is listed in the database Research Infrastructure Portal: RIsources of the German Research Foundation (DFG). For more details see here.

Publications with LIC infrastructure

Overview of scientific publications from research groups done by using LIC infrastructure and support

The chart is dynamically updated during our accounting procedures and therefore reflects the most recent publication statistics of the LIC facility. 

 

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Latest LIC User Statistics

 

We are happy to share the latest user statistics of the LIC facility within the MIAP framework. The charts are dynamically updated during our accounting procedures and therefore reflect the most recent user statistics of LIC. 

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Publications

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2020

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Author

Journal

DOI

Bsx Is Essential for Differentiation of Multiple Neuromodulatory Cell Populations in the Secondary Prosencephalon Schredelseker T, Veit F, Dorsky RI, Driever W. Front Neurosci. 2020 Jun 3;14:525. 10.3389/fnins.2020.00525
Cortical activity at different time scales: high-pass filtering separates motor planning and execution. Eriksson, D., Heiland, M., Schneider, A. & Diester, I. BioRxiv. DOI: https://doi.org/10.1101/857300 BioRxiv. DOI: https://doi.org/10.1101/857300
Force-responsive Zyxin modulation in periodontal ligament cells is regulated by YAP rather than TAZ. Belgardt E, Steinberg T, Husari A, Dieterle MP, Hülter-Hassler D, Jung B, Tomakidi P. Cell Signal. 2020 Aug;72:109662. 10.1016/j.cellsig.2020.109662
Conserved Genoarchitecture of the Basal Hypothalamus in Zebrafish Embryos Schredelseker T, Driever W. Front Neuroanat. 2020 Feb 6;14:3. 10.3389/fnana.2020.00003
A changing signaling environment induces multiciliated cell trans-differentiation during developmental remodeling Alexia Tasca, Martin Helmstädter, Magdalena Brislinger, Maximilian Haas, Peter Walentek https://www.biorxiv.org 10.1101/2020.04.16.045401
Image-derived models of cell organization changes during differentiation and drug treatments Ruan X, Johnson GR, Bierschenk I, Nitschke R, Boerries M, Busch H, Murphy RF Mol Biol Cell. 2020 Mar 19;31(7):655-666 10.1091/mbc.E19-02-0080
A Joint Action in Times of Pandemic: The German BioImaging Recommendations for Operating Imaging Core Facilities During the SARS-Cov-2 Emergency Dietzel S, Ferrando-May E, Fried H, Kukat C, Naumann A, Nitschke R, Pasierbek P, Peychl J, Rasse TM, Schroth-Diez B, Stöckl MT, Terjung S, Thuenauer R, Tulok S, Weidtkamp-Peters S; German BioImaging-Society for Microscopy and Image Analysis. Cytometry A. 2020 Sep;97(9):882-886 10.1002/cyto.a.24178
The acetyltransferase p300 regulates NRF2 stability and localization Ganner A, Pfeiffer ZC, Wingendorf L, Kreis S, Klein M, Walz G, Neumann-Haefelin E. . Biochem Biophys Res Commun. 2020 Apr 16;524(4):895-902. 10.1016/j.bbrc.2020.02.006
Color vision in insects: insights from Drosophila Schnaitmann C, Pagni M, Reiff DF. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2020 Mar;206(2):183-198 10.1007/s00359-019-01397-3
Optogenetic control of gene expression in plants in the presence of ambient white light Ochoa-Fernandez R, Abel NB, Wieland FG, Schlegel J, Koch LA, Miller JB, Engesser R, Giuriani G, Brandl SM, Timmer J, Weber W, Ott T, Simon R, Zurbriggen MD. Nat Methods. 2020 Jul;17(7):717-725. 10.1038/s41592-020-0868-y
Metabolic profiling in human fibroblasts enables subtype clustering in glycogen storage disease Luciana Hannibal, Jule Theimer, Victoria Wingert, Katharina Klotz, Iris Bierschenk, Roland Nitschke, Ute Spiekerkoetter, Sarah C Grünert Frontiers in Endocrinology, section Cellular Endocrinology in press
The Medicago truncatula DREPP Protein Triggers Microtubule Fragmentation in Membrane Nanodomains during Symbiotic Infections Su C, Klein ML, Hernández-Reyes C, Batzenschlager M, Ditengou FA, Lace B, Keller J, Delaux PM, Ott T. Plant Cell. 2020 May;32(5):1689-1702. 10.1105/tpc.19.00777
Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling Pous L, Deshpande SS, Nath S, Mezey S, Malik SC, Schildge S, Bohrer C, Topp K, Pfeifer D, Fernández-Klett F, Doostkam S, Galanakis DK, Taylor V, Akassoglou K, Schachtrup C. Nat Commun. 2020 Jan 31;11(1):630 10.1038/s41467-020-14466-y

2019

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Author

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DOI

Phytochrome-Based Extracellular Matrix with Reversibly Tunable Mechanical Properties. Hörner M, Raute K, Hummel B, Madl J, Creusen G, Thomas OS, Christen EH, Hotz N, Gübeli RJ, Engesser R, Rebmann B, Lauer J, Rolauffs B, Timmer J, Schamel WWA, Pruszak J, Römer W, Zurbriggen MD, Friedrich C, Walther A, Minguet S, Sawarkar R, Weber W. Adv Mater. 2019 Mar;31(12) 10.1002/adma.201806727
Optogenetic control of integrin-matrix interaction. Baaske J, Mühlhäuser WWD, Yousefi OS, Zanner S, Radziwill G, Hörner M, Schamel WWA, Weber W. Commun Biol. 2019 Jan 8;2:15 10.1038/s42003-018-0264-7
U-Net: deep learning for cell counting, detection, and morphometry. Falk T, Mai D, Bensch R, Çiçek Ö, Abdulkadir A, Marrakchi Y, Böhm A, Deubner J, Jäckel Z, Seiwald K, Dovzhenko A, Tietz O, Bosco CD, Walsh S, Saltukoglu D, Tay TL, Prinz M, Palme K, Simons M, Diester I, Brox T, Ronneberger O. Nat Methods. 2019 Jan;16(1):67-70 10.1038/s41592-019-0356-4
JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress. Cosolo A, Jaiswal J, Csordás G, Grass I, Uhlirova M, Classen AK Elife. 2019 Feb 8;8:e41036. 10.7554/eLife.41036
Auxin-Induced Plasma Membrane Depolarization Is Regulated by Auxin Transport and Not by AUXIN BINDING PROTEIN1. Paponov IA, Dindas J, Król E, Friz T, Budnyk V, Teale W, Paponov M, Hedrich R, Palme K. Front Plant Sci. 2019 Jan 17;9:1953. 10.3389/fpls.2018.01953
Response of Drosophila epithelial cell and tissue shape to external forces in vivo Balaji R, Weichselberger V, Classen AK. Development. 2019 Sep 6;146(17 10.1242/dev.171256
TBC1D8B Mutations Implicate RAB11-Dependent Vesicular Trafficking in the Pathogenesis of Nephrotic Syndrome Kampf LL, Schneider R, Gerstner L, Thünauer R, Chen M, Helmstädter M, Amar A, Onuchic-Whitford AC, Loza Munarriz R, Berdeli A, Müller D, Schrezenmeier E, Budde K, Mane S, Laricchia KM, Rehm HL, MacArthur DG, Lifton RP, Walz G, Römer W, Bergmann C, Hildebrandt F, Hermle T. J Am Soc Nephrol. 2019 Dec;30(12):2338-2353. 10.1681/ASN.2019040414
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria Teumer A, Li Y, Ghasemi S, Prins BP, Wuttke M, Hermle T, Giri A, Sieber KB, Qiu C, Kirsten H, Tin A, Chu AY, Bansal N, Feitosa MF, Wang L, Chai JF, Cocca M, Fuchsberger C, Gorski M, Hoppmann A, Horn K, Li M, Marten J, Noce D, Nutile T, Sedaghat S, Sveinbjornsson G, Tayo BO, van der Most PJ, Xu Y, Yu Z, Gerstner L, Ärnlöv J, Bakker SJL, Baptista D, Biggs ML, Boerwinkle E, Brenner H, Burkhardt R, Carroll RJ, Chee ML, Chee ML, Chen M, Cheng CY, Cook JP, Coresh J, Corre T, Danesh J, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Degenhardt F, Dittrich K, Divers J, Eckardt KU, Ehret G, Endlich K, Felix JF, Franco OH, Franke A, Freedman BI, Freitag-Wolf S, Gansevoort RT, Giedraitis V, Gögele M, Grundner-Culemann F, Gudbjartsson DF, Gudnason V, Hamet P, Harris TB, Hicks AA, Holm H, Foo VHX, Hwang SJ, Ikram MA, Ingelsson E, Jaddoe VWV, Jakobsdottir J, Josyula NS, Jung B, Kähönen M, Khor CC, Kiess W, Koenig W, Körner A, Kovacs P, Kramer H, Krämer BK, Kronenberg F, Lange LA, Langefeld CD, Lee JJ, Lehtimäki T, Lieb W, Lim SC, Lind L, Lindgren CM, Liu J, Loeffler M, Lyytikäinen LP, Mahajan A, Maranville JC, Mascalzoni D, McMullen B, Meisinger C, Meitinger T, Miliku K, Mook-Kanamori DO, Müller-Nurasyid M, Mychaleckyj JC, Nauck M, Nikus K, Ning B, Noordam R, Connell JO, Olafsson I, Palmer ND, Peters A, Podgornaia AI, Ponte B, Poulain T, Pramstaller PP, Rabelink TJ, Raffield LM, Reilly DF, Rettig R, Rheinberger M, Rice KM, Rivadeneira F, Runz H, Ryan KA, Sabanayagam C, Saum KU, Schöttker B, Shaffer CM, Shi Y, Smith AV, Strauch K, Stumvoll M, Sun BB, Szymczak S, Tai ES, Tan NYQ, Taylor KD, Teren A, Tham YC, Thiery J, Thio CHL, Thomsen H, Thorsteinsdottir U, Tönjes A, Tremblay J, Uitterlinden AG, van der Harst P, Verweij N, Vogelezang S, Völker U, Waldenberger M, Wang C, Wilson OD, Wong C, Wong TY, Yang Q, Yasuda M, Akilesh S, Bochud M, Böger CA, Devuyst O, Edwards TL, Ho K, Morris AP, Parsa A, Pendergrass SA, Psaty BM, Rotter JI, Stefansson K, Wilson JG, Susztak K, Snieder H, Heid IM, Scholz M, Butterworth AS, Hung AM, Pattaro C, Köttgen A. Nat Commun. 2019 Sep 11;10(1):4130. 10.1038/s41467-019-11576-0
?N-Tp63 Mediates Wnt/ß-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia. Haas M, Gómez Vázquez JL, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P. Cell Rep. 2019 Sep 24;28(13):3338-3352.e6. 10.1016/j.celrep.2019.08.063
Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling. Kvainickas A, Nägele H, Qi W, Dokládal L, Jimenez-Orgaz A, Stehl L, Gangurde D, Zhao Q, Hu Z, Dengjel J, De Virgilio C, Baumeister R, Steinberg F. J Cell Biol. 2019 Sep 2;218(9):3019-3038. 10.1083/jcb.201812110
Rapid spheroid clearing on a microfluidic chip Silva Santisteban T, Rabajania O, Kalinina I, Robinson S, Meier M. Lab Chip. 2017 Dec 19;18(1):153-161 10.1039/c7lc01114h
CBP-1/p300 acetyltransferase regulates SKN-1/Nrf cellular levels, nuclear localization, and activity in C. elegans Ganner A, Gerber J, Ziegler AK, Li Y, Kandzia J, Matulenski T, Kreis S, Breves G, Klein M, Walz G, Neumann-Haefelin E. Exp Gerontol, 2019 Oct 15;126:110690. 10.1016/j.exger.2019.110690
Divergent function of polycystin 1 and polycystin 2 in cell size regulation Viau A, Kotsis F, Boehlke C, Braeg S, Klein M, Nitschke R, Walz G, Kuehn EW. Biochem Biophys Res Commun. 2020 Jan 8;521(2):290-295 10.1016/j.bbrc.2019.10.074
AWD regulates timed activation of BMP signaling in intestinal stem cells to maintain tissue homeostasis Tracy Cai X, Li H, Safyan A, Gawlik J, Pyrowolakis G, Jasper H. Nat Commun. 2019 Jul 5;10(1):2988. 10.1038/s41467-019-10926-2
A GmNINa-miR172c-NNC1 Regulatory Network Coordinates the Nodulation and Autoregulation of Nodulation Pathways in Soybean Wang L, Sun Z, Su C, Wang Y, Yan Q, Chen J, Ott T, Li X. Mol Plant. 2019 Sep 2;12(9):1211-1226. 10.1016/j.molp.2019.06.002
Sequence environment of BMP-dependent activating elements controls transcriptional responses to Dpp signaling in Drosophila Chayengia M, Veikkolainen V, Jevtic M, Pyrowolakis G. Development 2019 146: dev176107 10.1242/dev.176107
Mitochondrial Perturbations Couple mTORC2 to Autophagy in C. elegans Aspernig H, Heimbucher T, Qi W, Gangurde D, Curic S, Yan Y, Donner von Gromoff E, Baumeister R, Thien A. Cell Rep. 2019 Nov 5;29(6):1399-1409.e5. 10.1016/j.celrep.2019.09.072
Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation Jordão MJC, Sankowski R, Brendecke SM, Sagar, Locatelli G, Tai YH, Tay TL, Schramm E, Armbruster S, Hagemeyer N, Groß O, Mai D, Çiçek Ö, Falk T, Kerschensteiner M, Grün D, Prinz M. Science. 2019 Jan 25;363(6425):eaat7554 10.1126/science.aat7554
Optogenetic control of integrin-matrix interaction Baaske J, Mühlhäuser WWD, Yousefi OS, Zanner S, Radziwill G, Hörner M, Schamel WWA, Weber W. Commun Biol. 2019 Jan 8;2:15. 10.1038/s42003-018-0264-7

2018

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Journal

DOI

U-Net: deep learning for cell counting, detection and morphometrie. Falk T, Mai D, Bensch R, Çiçek Ö, Abdulkadir A, Marrakchi Y, Böhm A, Deubner J, Jäckel Z, Seiwald K, Dovzhenko A, Tietz O, Bosco CD, Walsh S, Saltukoglu D, Tay TL, Prinz M, Palme K, Simons M, Diester I, Brox T, Ronneberger O. Nat Methods. 2019 Jan;16(1):67-70 10.1038/s41592-019-0356-4.
A PLA-iRoCS Pipeline for the Localization of Protein-Protein Interactions In Situ. Pasternak T, Teale W, Falk T, Ruperti B, Palme K. Methods Mol Biol. 2018;1787:161-170. 10.1007/978-1-4939-7847-2_12
AFM Imaging Suggests Receptor Free Penetration of Lipid Bilayers by Toxins. Brander S, Jank T, Hugel T. Langmuir. 2019 Jan 15;35(2):365-371. 10.1021/acs.langmuir.8b03146
Auxin-Induced Plasma Membrane Depolarization Is Regulated by Auxin Transport and Not by AUXIN BINDING PROTEIN1 Paponov IA, Dindas J, Król E, Friz T, Budnyk V, Teale W, Paponov M, Hedrich R, Palme K Front Plant Sci. 2018; 9: 1953. 10.3389/fpls.2018.01953
Bsx controls Pineal Complex Development. Schredelseker, T. and W. Driever Development 2018 145 10.1242/dev.163477
Cardiac Electrophysiological Effects of Light-Activated Chloride Channels. Kopton RA, Baillie JS, Rafferty SA, Moss R, Zgierski-Johnston CM, Prykhozhij SV, Stoyek MR, Smith FM, Kohl P, Quinn TA, Schneider-Warme F. Front Physiol. 2018 Dec 17;9:1806 10.3389/fphys.2018.01806
Cell cycle controls stress response and longevity in C. elegans. Dottermusch M, Lakner T, Peyman T, Klein M, Walz G, Neumann-Haefelin E. Aging (Albany NY). 2016 Sep 25;8(9):2100-2126. 10.18632/aging.101052
CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in C. elegans. Li Y, Finkbeiner S, Ganner A, Gerber J, Klein M, Grafe M, Kandzia J, Thien A, Thedieck K, Breves G, Jank T, Baumeister R, Walz G, Neumann-Haefelin E. Oncotarget. 2018 Jan 6;9(11):9581-9595. 10.18632/oncotarget.24039
Characterization of auxin transporter PIN6 plasma membrane targeting reveals a function for PIN6 in plant bolting. Ditengou FA, Gomes D, Nziengui H, Kochersperger P, Lasok H, Medeiros V, Paponov IA, Nagy SK, Nádai TV, Mészáros T, Barnabás B, Ditengou BI, Rapp K, Qi L, Li X, Becker C, Li C, Dóczi R, Palme K. New Phytol. 2018 Mar;217(4):1610-1624. 10.1111/nph.14923
Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney Viau A, Bienaimé F, Lukas K, Todkar AP, Knoll M, Yakulov TA, Hofherr A, Kretz O, Helmstaedter M, Reichardt W, Braeg S, Aschman T, Merkle A, Pfeifer D, Dumit VI, Gubler M-C, Nitschke R, Huber TB, Terzi F, Dengjel J, Grahammer F, Köttgen M, Busch H, Boerries M, Walz G, Triantafyllopoulou A, and Kuehn EW. EMBO J. 2018 Aug 1;37(15):e98615 10.15252/embj.201798615
Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney. Viau A, Bienaimé F, Lukas K, Todkar AP, Knoll M, Yakulov TA, Hofherr A, Kretz O, Helmstädter M, Reichardt W, Braeg S, Aschman T, Merkle A, Pfeifer D, Dumit VI, Gubler MC, Nitschke R, Huber TB, Terzi F, Dengjel J, Grahammer F, Köttgen M, Busch H, Boerries M, Walz G, Triantafyllopoulou A, Kuehn EW. EMBO J. 2018 Aug 1;37(15):e98615 10.15252/embj.201798615
Color Processing in the Early Visual System of Drosophila. Schnaitmann C, Haikala V, Abraham E, Oberhauser V, Thestrup T, Griesbeck O and Reiff DF Cell 2018 Jan 11;172(1-2):318-330 10.1016/j.cell.2017.12.018
Commonalities and Differences in Controlling Multipartite Intracellular Infections of Legume Roots by Symbiotic Microbes Lace B, Ott T Plant Cell Physiol. 2018 Apr 1;59(4):661-672 10.1093/pcp/pcy043
Computational 3D imaging to quantify structural components and assembly of protein networks. Asgharzadeh P, Özdemir B, Reski R, Röhrle O, Birkhold AI. Acta Biomater. 2018 Mar 15;69:206-217 10.1016/j.actbio.2018.01.020
Control of RAB7 activity and localization through the retromer/TBC1D5 complex enables RAB7 dependent mitophagy. Jimenez-Orgaz AJ, Kvainickas A, Denner J, Eimer S, Dengjel J, Steinberg F EMBO J., (2018)37:235-254 10.15252/embj.201797128
CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury Toma A. Yakulov, Abhijeet P. Todkar, Krasimir Slanchev, Johannes Wiegel, Alexandra Bona, Martin Groß, Alexander Scholz, Isabell Hess, Anne Wurditsch, Florian Grahammer, Tobias B. Huber, Virginie Lecaudey, Tillmann Bork, Jochen Hochrein, Melanie Boerries, Justine Leenders, Pascal de Tullio, François Jouret, Albrecht Kramer-Zucker & Gerd Walz Nat Commun 9, 3660 (2018) 0.1038/s41467-018-06094-4
CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury Yakulov TA, Todkar AP, Slanchev K, Wiegel J, Bona A, Groß M, Scholz A, Hess I, Wurditsch A, Grahammer F, Huber TB, Lecaudey V, Bork T, Hochrein J, Boerries M, Leenders J, de Tullio P, Jouret F, Kramer-Zucker Nat Commun. 2018 Sep 10;9(1):3660. doi: 10.1038/s41467-018-06094-4 10.1038/s41467-018-06094-4
Cytological analysis and structural quantification of FtsZ1-2 and FtsZ2-1 network characteristics in Physcomitrella patens Özdemir B, Asgharzadeh P, Birkhold AI, Mueller SJ, Röhrle O, Reski R. Sci Rep 8, 11165 (2018) 10.1038/s41598-018-29284-y
Extracellular bone morphogenetic protein modulator BMPER and twisted gastrulation homolog 1 preserve arterial venous specification in zebrafish blood vessel development and regulate Notch signaling in endothelial cells. Esser JS, Steiner RE, Deckler M, Schmitt H, Engert B, Link S, Charlet A, Patterson C, Bode C, Zhou Q, Moser M. FEBS J. 2018 Apr;285(8):1419-1436. 10.1111/febs.14414
Functional Analysis of the Arabidopsis thaliana CDPK-Related Kinase Family: AtCRK1 Regulates Responses to Continuous Light. Baba AI, Rigó G, Ayaydin F, Rehman AU, Andrási N, Zsigmond L, Valkai I, Urbancsok J, Vass I, Pasternak T, Palme K, Szabados L, Cséplo Á. Int J Mol Sci. 2018 Apr 25;19(5). pii: E1282. doi: 10.3390/ijms19051282. 10.3390/ijms19051282
GAPVD1 and ANKFY1 Mutations Implicate RAB5 Regulation in Nephrotic Syndrome Hermle T, Schneider R, Schapiro D, Braun DA, van der Ven AT, Warejko JK, Daga A, Widmeier E, Nakayama M, Jobst-Schwan T, Majmundar AJ, Ashraf S, Rao J, Finn LS, Tasic V, Hernandez JD, Bagga A, Jalalah SM, El Desoky S, Kari JA, Laricchia KM, Lek M, Rehm HL, MacArthur DG, Mane S, Lifton RP, Shril S, Hildebrandt F. J Am Soc Nephrol. 2018 Aug;29(8):2123-2138. doi: 10.1681/ASN.2017121312.
Generic and reversible opto-trapping of biomolecules. Beyer HM, Thomas OS, Riegel N, Zurbriggen MD, Weber W, Hörner M. Acta Biomater. 2018 Oct 1;79:276-282 10.1016/j.actbio.2018.08.032
Hydrogen Sulfide Exerts Anti-oxidative and Anti-inflammatory Effects in Acute Lung Injury. Zimmermann KK, Spassov SG, Strosing KM, Ihle PM, Engelstaedter H, Hoetzel A, Faller S. Inflammation. 2018 Feb;41(1):249-259 10.1007/s10753-017-0684-4
Insight into nuclear body formation of phytochromes through stochastic modelling and experiment. Ramon Grima, Sebastian Sonntag, Filippo Venezia, Stefan Kircher, Robert W Smith and Christian Fleck Phys Biol. 2018 May 18;15(5):056003. 10.1088/1478-3975/aac193
Interplay of the two ancient metabolites auxin and MEcPP regulates adaptive growth. Jiang J, Rodriguez-Furlan C, Wang JZ, de Souza A, Ke H, Pasternak T, Lasok H, Ditengou FA, Palme K, Dehesh K. Nat Commun. 2018 Jun 11;9(1):2262. 10.1038/s41467-018-04708-5
Maternal Nanog is required for zebrafish embryo architecture and for cell viability during gastrulation. Veil M, Schaechtle MA, Gao M, Kirner V, Buryanova L, Grethen R, Onichtchouk D. Development. 2018 Jan 9;145(1):dev155366. 10.1242/dev.155366
Na+/H+ exchangers are required for development and function of vertebrate mucociliary epithelia Sun DI, Tasca A, Haas M, Baltazar G, Harland RM, Finkbeiner WE, Walentek P. Cells Tissues Organs. 2018;205(5-6):279-292. 10.1159/000492973
Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Sun DI, Tasca A, Haas M, Baltazar G, Harland RM, Finkbeiner WE, Walentek P. Cells Tissues Organs 2018;205:279–292 10.1159/000492973
Progesterone modulates microtubule dynamics and epiboly progression during zebrafish gastrulation. Eckerle S, Ringler M, Lecaudey V, Nitschke R, Driever W. Dev Biol. 2018 Feb 15;434(2):249-266 https://www.sciencedirect.com/science/article/pii/S0012160617307157?via%3Dihub
Projections of the Diencephalospinal Dopaminergic System to Peripheral Sense Organs in Larval Zebrafish (Danio rerio). Haehnel-Taguchi, M., Fernandes, A.M., Böhler, M., Schmitt, I., Tittel, L., and Driever, W. Front. Neuroanat. 12, 191.
Root Gravitropism Is Regulated by a Crosstalk between para-Aminobenzoic Acid, Ethylene, and Auxin. Nziengui H, Lasok H, Kochersperger P, Ruperti B, Rébeillé F, Palme K, Ditengou FA. Plant Physiol. 2018 Nov;178(3):1370-1389. 10.1104/pp.18.00126
Sevoflurane posttreatment prevents oxidative and inflammatory injury in ventilator-induced lung injury. Wagner J, Strosing KM, Spassov SG, Lin Z, Engelstaedter H, Tacke S, Hoetzel A, Faller S. PLoS One. 2018 Feb 22;13(2):e0192896 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192896
Symbiotic root infections in Medicago truncatula require remorin-mediated receptor stabilization in membrane nanodomains Liang P, Stratil TF, Popp C, Marin M, Folgmann J, Mysore KS, Wen J, Ott T Proc Natl Acad Sci U S A. 2018 May 15;115(20):5289-5294 10.1073/pnas.1721868115
Symbiotic root infections in Medicago truncatula require remorin-mediated receptor stabilization in membrane nanodomains. Liang P, Stratil TF, Popp C, Marín M, Folgmann J, Mysore KS, Wen J, Ott T. Proc Natl Acad Sci U S A. 2018 May 15;115(20):5289-5294 10.1073/pnas.1721868115
The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism Hofherr A, Seger C, Fitzpatrick F, Busch T, Michel E, Luan J, Osterried L, Linden F, Kramer-Zucker A, Wakimoto B, Schütze C, Wiedemann N, Artati A, Adamski J, Walz G, Kunji ERS, Montell C, Watnick T, Köttgen M. PLoS Biol. 2018 Aug 6;16(8):e2005651 10.1371/journal.pbio.2005651
The nucleoside-diphosphate kinase NME3 associates with nephronophthisis proteins and is required for ciliary function during renal development. Hoff S, Epting D, Falk N, Schroda S, Braun DA, Halbritter J, Hildebrandt F, Kramer-Zucker A, Bergmann C, Walz G, Lienkamp SS J Biol Chem. 2018 Sep 28;293(39):15243-15255. 10.1074/jbc.RA117.000847

2017

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DOI

3D analysis of mitosis distribution highlights the longitudinal zonation and diarch symmetry in proliferation activity of the Arabidopsis thaliana root meristem. Lavrekha VV, Pasternak T, Ivanov VB, Palme K, Mironova VV. Plant J. 2017 Dec;92(5):834-845. 10.1111/tpj.13720
A 3D digital atlas of the Nicotiana tabacum root tip and its use to investigate changes in the root apical meristem induced by the Agrobacterium 6b oncogene. Pasternak T, Haser T, Falk T, Ronneberger O, Palme K, Otten L. Plant J. 2017 Oct;92(1):31-42. doi: 10.1111/tpj.13631. Epub 2017 Aug 11. 10.1111/tpj.13631
A Dual-Fluorescence Reporter in the Eomes Locus for Live Imaging and Medium-Term Lineage Tracing, Probst, S., Daza, R., Bader, N., Hummel, J.F., Weiß, M., Tanriver, Y., Hevner, R.F., Arnold, S.J. Genesis. 2017 Aug;55(8):10.1002/dvg.23043 10.1002/dvg.23043
A Functional Gradient in the Rodent Prefrontal Cortex Supports Behavioral Inhibition Hardung S., Epple R., Jaeckel Z., Eriksson D., Uran C., Senn V., Gibor L., Yizhar O., Diester I Curr Biol 2017 Feb 20;27(4):549-555. 10.1016/j.cub.2016.12.052
A method for characterizing phenotypic changes in highly variable cell populations and its application to high content screening of Arabidopsis thaliana protoplasts. Johnson GR, Kangas JD, Dovzhenko A, Trojok R, Voigt K, Majarian TD, Palme K, Murphy RF. Cytometry A. 2017 Apr;91(4):326-335. 10.1002/cyto.a.23067
A molecular framework for the embryonic initiation of shoot meristem stem cells. Developmental Cell Zhang, Z., Tucker, E., Hermann, M, Laux, T. Developmental Cell, 40, 264–277. 10.1016/j.devcel.2017.01.002
A phenol-enriched cuticle is ancestral to lignin evolution in land plants. Renault, H., A. Alber, N.A. Horst, A.B. Lopes, E.A. Fich, L. Kriegshauser, G. Wiedemann, P. Ullmann, L. Herrgott, M. Erhardt, E. Pineau, J. Ehlting, M. Schmitt, J.K.C. Rose, R. Reski, D. Werck-Reichhart Nature Communications 8, 14713. 10.1038/ncomms14713
A Toolbox for Optophysiological Experiments in Freely Moving Rats Hardung S, Alyahyay M, Eriksson D, Diester I Front Syst Neurosci . 2017 May 11;11:27. 10.3389/fnsys.2017.00027
Absence of the integrin a3 subunit induces an activated phenotype in human keratinocytes. Pazzagli C, He Y, Busch H, Esser P, Kiritsi D, Gache Y, Bruckner-Tuderman L, Boerries M, Has C. J Invest Dermatol 137:1387-1391, 2017 10.1016/j.jid.2017.01.018
Amino acid duplication in the coiled-coil structure of collagen XVII alters its maturation and trimerization causing mild junctional epidermolysis bullosa Kroeger JK, Hofmann SC, Leppert J, Has C*#, Hum Mol Genet 1;26:479-488, 2017 10.1093/hmg/ddw404
Bipolar cell gap junctions serve major signaling pathways in the human retina. Kántor O, Varga A, Nitschke R, Naumann A, Énzsöly A, Lukáts Á, Szabó A, Németh J, Völgyi B. Brain Struct Funct. 2017 Aug;222(6):2603-2624. 10.1007/s00429-016-1360-4
C. elegans DAF-16/FOXO interacts with TGF-ß/BMP signaling to induce germline tumor formation via mTORC1 activation. Qi W, Yan Y, Pfeifer D, Donner V Gromoff E, Wang Y, Maier W, Baumeister R. PLoS Genet. 2017 May 26;13(5):e1006801. 10.1371/journal.pgen.1006801
Cargo selective SNX-BAR proteins mediate retromer trimer independent retrograde transport. Kvainickas A, Jimenez-Orgaz AJ, Nägele H, Dengjel J, Steinberg F J Cell Biol, 2017, Nov 6. 10.1083/jcb.201702137
Das Plastidenskelett: ein Ideengeber im nano-Bereich. Özdemir, B., P. Asgharzadeh, A. Birkhold, O. Röhrle, R. Reski In: J. Knippers, U. Schmid, T. Speck (Eds.) Baubionik - Biologie beflügelt Architektur. Stuttgarter Beiträge zur Naturkunde (Hrsg. Staatliches Museum für Naturkunde Stuttgart), Serie C, Band 82, 153 Seiten. Stuttgart. ISSN 0341-0161, pp. 121-124.
Degradation of protein translation machinery by amino acid starvation-induced macroautophagy. Gretzmeier C, Eiselein S, Johnson GR, Engelke R, Nowag H, Zarei M, Küttner V, Becker AC, Rigbolt KTG, Høyer-Hansen M, Andersen JS, Münz C, Murphy RF, Dengjel J. Autophagy. 2017 Jun 3;13(6):1064-1075. 10.1080/15548627.2016.1274485
Early tissue damage and microstructural reorganization predict disease severity in experimental epilepsy. Janz P, Schwaderlapp N, Heining K, Häussler U, Korvink JG, von Elverfeldt D, Hennig J, Egert U, LeVan P, Haas CA. Elife. 2017 Jul 26;6:e25742. 10.7554/eLife.25742
Gene regulation during Drosophila eggshell patterning. Pyrowolakis G, Veikkolainen V, Yakoby N, Shvartsman SY. Proc Natl Acad Sci USA, 114 (23), 5808-13, 2017 10.1073/pnas.1610619114
Homozygous Nonsense Mutation and Additional Deletion of an Amino Acid in BPAG1e Causing Mild Localized Epidermolysis Bullosa Simplex. He Y, Leppert J, Steinke H, Has C. Acta Derm Venereol 97:657-659, 2017 10.2340/00015555-2618
Hydrogen Sulfide Prevents Formation of Reactive Oxygen Species through PI3K/Akt Signaling and Limits Ventilator-Induced Lung Injury. Spassov SG, Donus R, Ihle PM, Engelstaedter H, Hoetzel A, Faller S. Oxid Med Cell Longev. 2017;2017:3715037. 10.1155/2017/3715037
Large deletions targeting the triple-helical domain of collagen VII lead to mild acral dominant dystrophic epidermolysis bullosa. Chmel N, Bornert O, Hausser I, Grüninger G, Borozkin W, Kohlhase J, Nyström A, Has C. J Invest Dermatol. 2018 Apr;138(4):987-991Epub 2017 Nov 24. 10.1016/j.jid.2017.11.014
Microscopy of Physcomitrella patens sperm cells. Horst, N., R. Reski Plant Methods. 2017 May 10;13:33 10.1186/s13007-017-0186-2
Monoallelic large intragenic KRT5 deletions account for genetically unsolved cases of epidermolysis bullosa simplex. Has C, Schumann H, Leppert J, He Y, Hartmann B, Hausser I, Kohlhase J. J Invest Dermatol. 137(10):2231-2234, 2017 10.1016/j.jid.2017.05.016
Optogenetic targeting of cardiac myocytes and non-myocytes: Tools, challenges and utility. Johnston CM, Rog-Zielinska EA, Wülfers EM, Houwaart T, Siedlecka U, Naumann A, Nitschke R, Knöpfel T, Kohl P, Schneider-Warme F. Prog Biophys Mol Biol. 2017 Nov;130(Pt B):140-149 10.1016/j.pbiomolbio.2017.09.014
Parkin promotes proteasomal degradation of misregulated Bax. Cakir, Z., Lauterwasser, J., Todt, F., Funk, K., Zerbes, R.M., Ölgeklaus, A., Tanaka, A., van der Laan, M., Edlich, F. J Cell Sci. 2017 Sep 1;130(17):2903-2913 10.1242/jcs.200162
PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Ruf S, Heberle AM, Langelaar-Makkinje M, Gelino S, Wilkinson D, Gerbeth C, Schwarz JJ, Holzwarth B, Warscheid B, Meisinger C, van Vugt MA, Baumeister R, Hansen M, Thedieck K. Autophagy. 2017 Mar 4;13(3):486-505. 10.1080/15548627.2016.1263781
Pre- and posttreatment with hydrogen sulfide prevents ventilator-induced lung injury by limiting inflammation and oxidation. Faller S, Seiler R, Donus R, Engelstaedter H, Hoetzel A, Spassov SG. PLoS One. 2017 Oct 11;12(10):e0186532. 10.1371/journal.pone.0186532
Respiratory status determines the effect of emodin on cell viability. Dumit VI, Zerbes RM, Kaeser-Pebernard S, Rackiewicz M, Wall MT, Gretzmeier C, Küttner V, van der Laan M, Braun RJ, Dengjel J. Oncotarget. 2017 Jun 6;8(23):37478-37490. 10.18632/oncotarget.16396
RETINOBLASTOMA RELATED1 mediates germline entry in Arabidopsis. Zhao X., Bramsiepe J., Van Durme M., Komaki S., Prusicki M.A., Maruyama D., Forner J., Medzihradszky A., Wijnker E., Harashima H., Lu Y., Schmidt A., Guthörl D., Logroño R.S., Guan Y., Pochon G.1, Grossniklaus U., Laux T., Higashiyama T., Lohmann J.U., Nowack M.K. and Schnittger A. Science. 2017 Apr 28;356(6336):eaaf6532 10.1126/science.aaf6532
Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling. McNally KE, Faulkner R, Steinberg F, Gallon M, Ghai R, Pim D, Langton P, Pearson N, Danson CM, Nägele H, Morris LL, Singla A, Overlee BL, Heesom KJ, Sessions R, Banks L, Collins BM, Berger I, Billadeau DD, Burstein E, Cullen PJ. Nat Cell Biol. 2017 Oct;19(10):1214-1225 10.1038/ncb3610
Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50. Kvainickas A, Orgaz AJ, Nägele H, Diedrich B, Heesom KJ, Dengjel J, Cullen PJ, Steinberg F. J Cell Sci. 2017 Jan 15;130(2):382-395 10.1242/jcs.196758
Role of influenza a virus NP acetylation on viral growth and replication. Giese S, Ciminski K, Bolte H, Moreira ÉA, Lakdawala S, Hu Z, David Q, Kolesnikova L, Götz V, Zhao Y, Dengjel J, Chin YE, Xu K, Schwemmle M. Nat Commun. 2017 Nov 2;8(1):1259 10.1038/s41467-017-01112-3
Sex-specific transcript diversity in the fly brain is established during pupal stages and adulthood and is largely independent of the mating process and the germ line. Mohr C, Kleiner S, Blanchette M, Pyrowolakis G, Hartmann B. Sex Dev, 11(2):94-108, 2017 10.1159/000456022
Specific role of RhoC in tumor invasion and metastasis. Lang S, Busch H, Boerries M, Brummer T, Timme S, Lassmann S, Aktories K, Schmidt G Oncotarget, 2017. Sep 16;8(50):87364-87378 10.18632/oncotarget.20957
Synaptic remodeling of entorhinal input contributes to an aberrant hippocampal network in temporal lobe epilepsy. Janz P, Savanthrapadian S, Häussler U, Kilias A, Nestel S, Kretz O, Kirsch M, Bartos M, Egert U, Haas CA Cereb Cortex 27:2348-2364. 10.1093/cercor/bhw093
The Descending Diencephalic Dopamine System Is Tuned to Sensory Stimuli. Reinig, S., Driever, W. and Arrenberg, A. B. Current biology : CB 27, 318-333. 10.1016/j.cub.2016.11.059
The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier. Schell C, Rogg M, Suhm M, Helmstädter M, Sellung D, Yasuda-Yamahara M, Kretz O, Küttner V, Suleiman H, Kollipara L, Zahedi RP, Sickmann A, Eimer S, Shaw AS, Kramer-Zucker A, Hirano-Kobayashi M, Abe T, Aizawa S, Grahammer F, Hartleben B, Dengjel J, Huber TB. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4621-E4630. 10.1073/pnas.1617004114
The mitochondrial proteome of the moss Physcomitrella patens. Mueller, S.J., S.N.W. Hoernstein, R. Reski Mitochondrion. 2017 Mar;33:38-44. 10.1016/j.mito.2016.07.007
The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation. Esser JS, Charlet A, Schmidt M, Heck S, Allen A, Lother A, Epting D, Patterson C, Bode C and Moser M. Cardiovasc Res. 2017 Feb; 113: 222-223, IF: 5.878 10.1093/cvr/cvw248
Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote. Ueda, M., Aichinger, E., Gong, W., Groot, E., Verstraeten, I., Dai Vu, L., De Smet, I., Higashiyama, T., Umeda, M. and Laux, T. Genes Dev. 2017 Mar 15;31(6):617-627 10.1101/gad.292409.116
Whole transcriptome screening reveals myelination deficits in dysplastic human temporal neocortex. Donkels C, Pfeifer D, Janz P, Huber S, Nakagawa J, Prinz M, Schulze-Bonhage A, Weyerbrock A, Zentner J, Haas CA Cereb Cortex. 2017 Feb 1;27(2):1558-1572 10.1093/cercor/bhv346

2016

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3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation. Çiçek Ö, Abdulkadir A, Lienkamp SS, Brox T, and Ronneberger O Medical Image Computing and Computer-Assisted Intervention – MICCAI 2016: 19th International Conference, Athens, Greece, October 17-21, 2016,Proceedings, Part II 10.1007/978-3-319-46723-8_49, S. Ourselin, L. Joskowicz, M.R. Sabuncu, G. Unal, and W. Wells,
A detailed expression map of the PIN1 auxin transporter in Arabidopsis thaliana root. Omelyanchuk NA, Kovrizhnykh VV, Oshchepkova EA, Pasternak T, Palme K, Mironova VV. Plant Physiol. 2016 Jan;170(1):23-5 10.1186/s12870-015-0685-0
A single homeobox gene triggers phase transition, embryogenesis and asexual reproduction. Horst, N.A., A. Katz, I. Pereman, E.L. Decker, N. Ohad, R. Reski Nature Plants 2, 15209. 10.1038/nplants.2015.209
Analysis of confocal image data of Physcomitrella chloroplasts to reveal adaptation principles leading to structural stability at the nano scale. Asgharzadeh, P., B. Özdemir, Stefanie J. Müller, R. Reski, O. Röhrle Proceedings in Applied Mathematics and Mechanics 16, 69-70.
Analysis of Physcomitrella chloroplasts to reveal adaptation principles leading to structural stability at the nano-scale. Asgharzadeh, P., B. Özdemir, S.J. Mueller, O. Röhrle, R. Reski Biomimetic Research for Architecture and Building Construction: Biological Design and Integrative Structures (Eds.: J. Knippers, K. Nickel and T. Speck). Springer book series “Biologically-Inspired Systems” Volume 9 (Ed.: S.N. Gorb). Springer International Publishing AG, Switzerland, pp. 261-275.
Calcium buffer proteins are specific markers of human retinal neurons Kántor O, Mezey S, Adeghate J, Naumann A, Nitschke R, Énzsöly A, Szabó A, Lukáts Á, Németh J, Somogyvári Z, Völgyi B. Cell Tissue Res. 2016 Jul;365(1):29-50 10.1007/s00441-016-2376-z
Cardiac activation heat remains inversely dependent on temperature over the range 27-37 degrees C. Johnston CM, Han JC, Loiselle DS, Nielsen PM, Taberner AJ Am J Physiol-heart C,2016; 310 (11): H1512-H1519. 10.1152/ajpheart.00903.2015
Characterization of connexin36 gap junctions in the human outer retina. Kántor O, Benko Z, Énzsöly A, Dávid C, Naumann A, Nitschke R, Szabó A, Pálfi E, Orbán J, Nyitrai M, Németh J, Szél Á, Lukáts Á, Völgyi B. Brain Struct Funct. 2016 Jul;221(6):2963-84. 10.1007/s00429-015-1082-z
Characterization of photomorphogenic responses and signaling cascades controlled by phytochrome-A expressed in different tissues. Kirchenbauer D, Viczián A, Ádám É, Hegedus Z, Klose C, Leppert M, Hiltbrunner A, Kircher S, Schäfer E, Nagy F New Phytologist Volume 211, Issue 2 10.1111/nph.13941
Chloroplast FBPase and SPBase are thioredoxin-linked enzymes with similar architecture but different evolutionary histories. Gütle, D.D., T. Roret, S.J. Mueller, J. Couturier, S.D. Lemaire, A. Hecker, T. Dhalleine, B.B. Buchanan, R. Reski, O. Einsle, J.P. Jacquot Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):6779-84 10.1073/pnas.1606241113
Direct Reprogramming of Fibroblasts into Renal Tubular Epithelial Cells by Defined Transcription Factors. Kaminski M, Tosic J, Kresbach C, Engel H, Klockenbusche J, Müller A-L, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS. Nat Cell Biol. 2016 Dec;18(12):1269-1280 10.1038/ncb3437
Identification of targets and interaction partners of arginyl-tRNA protein transferase in the moss Physcomitrella patens. Hoernstein, S.N.W., S.J. Mueller, K. Fiedler, M. Schuelke, J.T. Vanselow, C. Schuessele, D. Lang, R. Nitschke, G.L. Igloi, A. Schlosser, R. Reski Mol Cell Proteomics. 2016 Jun;15(6):1808-22. 10.1074/mcp.M115.057190
Monoallelic Mutations in the Translation Initiation Codon of KLHL24 Cause Skin Fragility. He Y, Maier K, Leppert J, Hausser I, Schwieger-Briel A, Weibel L, Theiler M, Kiritsi D, Busch H, Boerries M, Hannula-Jouppi K, Heikkilä H, Tasanen K, Castiglia D, Zambruno G, Has C. Am J Hum Genet 99:1395-1404, 2016 10.1016/j.ajhg.2016.11.005
Origin and function of stomata in the moss Physcomitrella patens. Chater, C.C., R.S. Caine, M. Tomek, S. Wallace, Y. Kamisugi, A.C. Cuming, D. Lang, C.A. MacAlister, S. Casson, D.C. Bergmann, E.L. Decker, W. Frank, J.E. Gray, A. Fleming, R. Reski, D.J. Beerling Nat Plants. 2016 Nov 28;2:16179 10.1038/nplants.2016.179
Pentagone fine-tunes glypicans to regulate multiple signaling pathways. Norman M, Vuilleumier R, Springhorn A, Gawlik J, Pyrowolakis G. Elife. 2016 Jun 8;5:e13301 10.7554/eLife.13301
Single Amino Acid Deletion in Kindlin-1 Results in Partial Protein Degradation Which Can Be Rescued by Chaperone Treatment. Maier K, He Y, Esser PR, Thriene K, Sarca D, Kohlhase J, Dengjel J, Martin L, Has C. J Invest Dermatol. 2016 May;136(5):920-929. 10.1016/j.jid.2015.12.039
Spatio-temporal patterning of arginyl-tRNA protein transferase (ATE) contributes to gametophytic development in a moss. Schuessele, C., S.N.W. Hoernstein, S.J. Mueller, M. Rodriguez-Franco, T. Lorenz, D. Lang, G.L. Igloi, R. Reski New Phytol. 2016 Feb;209(3):1014-27 10.1111/nph.13656
The Polycomb group protein CLF emerges as a specific tri-methylase of H3K27 regulating gene expression and development in Physcomitrella patens. Pereman, I., A. Mosquna, A. Katz, G. Wiedemann, D. Lang, E.L. Decker, Y. Tamada, T. Ishikawa, T. Nishiyama, M. Hasebe, R. Reski, N. Ohad Biochim Biophys Acta. 2016 Jul;1859(7):860-70. 10.1016/j.bbagrm.2016.05.004
The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling. Raja E, Tzavlaki K, Vuilleumier R, Edlund K, Zieba A, Morén, Watanabe Y, Voytyuk I, Botling J, Söderberg O, Micke P, Pyrowolakis G, Heldin CH, Moustakas A Oncotarget, 7(2), 1120-43, 2016 10.18632/oncotarget.6683
UV-B-induced cutaneous inflammation and prospects for antioxidant treatment in Kindler syndrome. Maier K, He Y, Wölfle U, Esser PR, Brummer T, Schempp C, Bruckner-Tuderman L, Has C. Hum Mol Genet 25:5339-5352, 2016 10.1093/hmg/ddw350

2015

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A Cilia Independent Role of Ift88/Polaris during Cell Migration. Boehlke C, Janusch H, Hamann C, Powelske C, Mergen M, Herbst H, Kotsis F, Nitschke R, and Kuehn EW. PLoS One 10, e0140378 (2015) doi.org/10.1371/journal.pone.0140378
A disposable discrete-agent-release cartridge for flexible endoscopes N. Wangler, M. Welsche, G. Roth, N. Paust, R. Zengerle Proc. of the 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), Groningen, The Netherlands, October 3 – 10, 2010, pp.1205 – 1207
Anks3 interacts with nephronophthisis proteins and is required for normal renal development. Yakulov TA, Yasunaga T, Ramachandran H, Engel C, Muller B, Hoff S, Dengjel J, Lienkamp SS, Walz G Kidney Int. 2015 Jun;87(6):1191-200 10.1038/ki.2015.17
Astrocyte uncoupling as a cause of human temporal lobe epilepsy Bedner P, Dupper A, Hüttmann K, Müller J, Herde MK, Dublin P, Deshpande T, Schramm J, Häussler U, Haas CA, Henneberger C, Theis M, Steinhäuser C. Brain. 2015 May;138(Pt 5):1208-22 10.1093/brain/awv067
BMP-dependent gene repression cascade in Drosophila eggshell patterning. Charbonnier E, Fuchs A, Cheung LS, Chayengia M, Veikkolainen V, Seyfferth J, Shvartsman SY, Pyrowolakis G Dev Biol. 2015 Apr 15;400(2):258-65. 10.1016/j.ydbio.2015.02.004
BMP-dependent gene repression cascade in Drosophila eggshell patterning. Charbonnier E, Fuchs A, Cheung LS, Chayengia M, Shvartsman SY, Pyrowolakis G. Dev Biol. 2015 Apr 15;400(2):258-65 10.1016/j.ydbio.2015.02.004
B-Raf inhibitors induce epithelial differentiation in BRAF-mutant colorectal cancer cells. Herr R, Köhler M, Andrlová H, Weinberg F, Möller Y, Halbach S, Lutz L, Mastroianni J, Klose M, Bittermann N, Kowar S, Zeiser R, Olayioye MA, Lassmann S, Busch H, Boerries M, Brummer T. Cancer Res. 2015 Jan 1;75(1):216-29 10.1158/0008-5472.CAN-13-3686
Cell segmentation and tracking in phase contrast images using graph cut with asymmetric boundary costs Robert Bensch, Olaf Ronneberger IEEE International Symposium on Biomedical Imaging (ISBI), 2015
Crucial role of posttranslational modifications of integrin a3 in interstitial lung disease and nephrotic syndrome. Yalcin EG, He Y, Orhan D, Pazzagli C, Emiralioglu N, Has C. Hum Mol Genet. 2015 Jul 1;24(13):3679-88 10.1093/hmg/ddv111
Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells Funk, M.C., Bera, A.N., Menchen, T., Kuales, G., Thriene, K., Lienkamp, S.S., Dengjel, J., Omran, H., Frank, M., and Arnold, S.J. EMBO J. 2015 Apr 15;34(8):1078-89 10.15252/embj.201490805
Differential retrotranslocation of mitochondrial Bax and Bak. Todt F, Cakir Z, Reichenbach F, Emschermann F, Lauterwasser J, Kaiser A, Ichim G, Tait SW, Frank S, Langer HF, Edlich F EMBO J. 2015 Jan 2;34(1):67-80 10.15252/embj.201488806
Hantavirus infection with severe proteinuria and podocyte foot-process effacement. Boehlke C, Hartleben B, Huber TB, Hopfer H, Walz G, Neumann-Haefelin E. Am J Kidney Dis. 2014 Sep;64(3):452-6 10.1053/j.ajkd.2014.04.030
Identification of a new genomic hot spot of evolutionary diversification of protein function. Winkelmann A, You X, Grünewald N, Häussler U, Krestel H, Haas CA, Schwarz G, Chen W, Meier J. PLoS One. 2015 May 8;10(5) 10.1371/journal.pone.0125413
Mitochondrial Dynamics and the ER: The Plant Perspective. Mueller, S.J., R. Reski Front Cell Dev Biol. 2015 Dec 23;3:78 10.3389/fcell.2015.00078
Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains. Beck-García K, Beck-García E, Bohler S, Zorzin C, Sezgin E, Levental I, Alarcón B, Schamel WW Biochim Biophys Acta. 2015 Apr;1853(4):802-9 10.1016/j.bbamcr.2014.12.017
Organizer-Derived WOX5 Signal Maintains Root Columella Stem Cells through Chromatin-Mediated Repression of CDF4 Expression. Pi, L., Aichinger, E., van der Graaff, E., Llavata-Peris, C., Weijers, D., Hennig, L., Groot, E., and Laux, T. Developmental Cell 33, 576-88. 10.1016/j.devcel.2015.04.024
Stratified organization and disorganization of inner plexiform layer revealed by TNAP activity in healthy and diabetic rat retina. Kántor O, Varga A, Tóth R, Énzsöly A, Pálfi E, Kovács-Öller T, Nitschke R, Szél Á, Székely A, Völgyi B, Négyessy L, Somogyvári Z, Lukáts Á. Cell Tissue Res. 2015 Feb;359(2):409-421. 10.1007/s00441-014-2047-x
Systematic analysis of how phytochrome B dimerization determines its specificity. Klose C, Venezia F, Hussong A, Kircher S, Schäfer E, Fleck C. Nat Plants. 2015 Jul 6;1:15090 10.1038/nplants.2015.90
The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells. Yasunaga T, Hoff S, Schell C, Helmstadter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Muller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, and Walz G. J Cell Biol. 2015 Dec 7;211(5):963-73 10.1083/jcb.201502043
The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin. Epting D, Slanchev K, Boehlke C, Hoff S, Loges NT, Yasunaga T, Indorf L, Nestel S, Lienkamp SS, Omran H, Kuehn EW, Ronneberger O, Walz G, Kramer-Zucker A Development. 2015 Jan 1;142(1):174-84 10.1242/dev.112250
TSC1 Activates TGF-ß-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition. Thien A, Prentzell MT, Holzwarth B, Kläsener K, Kuper I, Boehlke C, Sonntag AG, Ruf S, Maerz L, Nitschke R, Grellscheid SN, Reth M, Walz G, Baumeister R, Neumann-Haefelin E, Thedieck K. Dev Cell. 2015 Mar 9;32(5):617-30 10.1016/j.devcel.2015.01.026
Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos. Jank, T., Eckerle, S., Steinemann, M., Trillhaase, C., Schimpl, M., Wiese, S., van, A. D. M., Driever, W. and Aktories, K. Nat Commun. 2015 Jul 20;6:7807. 10.1038/ncomms8807

2014

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A chemical switch for controlling viral infectivity Hörner M, Kaufmann B, Cotugno G, Wiedtke E, Büning H, Grimm D, Weber W Chem Commun (Camb). 2014 Sep 14;50(71):10319 10.1039/c4cc03292f
Accurate Detection in Volumetric Images using Elastic Registration based Validation D. Mai, J. Dürr, K. Palme, O. Ronneberger German Conference on Pattern Recognition (GCPR): 453--463, 2014
Caenorhabditis elegans OSM-11 signaling regulates SKN-1/Nrf during embryonic development and adult longevity and stress response. Dresen A, Finkbeiner S, Dottermusch M, Beume JS, Li Y, Walz G, Neumann-Haefelin E Dev Biol. 2015 Jan 29. pii: S0012-1606(15)00041-X. 10.1016/j.ydbio.2015.01.021
Changes in neural network homeostasis trigger neuropsychiatric symptoms. Winkelmann A, Maggio N, Eller J, Caliskan G, Semtner M, Häussler U, Jüttner R, Dugladze T, Smolinsky B, Kowalczyk S, Chronowska E, Schwarz G, Rathjen FG, Rechavi G, Haas CA, Kulik A, Gloveli T, Heinemann U, Meier JC. J Clin Invest. 2014 Feb;124(2):696-711. 10.1172/JCI71472
Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly Taschner M, Kotsis F, Braeuer P, Kuehn EW, Lorentzen E. J Cell Biol. 2014 Oct 27;207(2):269-82. 10.1083/jcb.201408002
Epilepsy-induced motility of differentiated neurons. Chai X, Münzner G, Zhao S, Tinnes S, Kowalski J, Häussler U, Young C, Haas CA, Frotscher M. Cereb Cortex. 2014 Aug;24(8):2130-40. doi: 10.1093/cercor/bht067. Epub 2013 Mar 15. 10.1093/cercor/bht067
Expression pattern and first functional characterization of riok-1 in Caenorhabditis elegans. Weinberg F, Schulze E, Fatouros C, Schmidt E, Baumeister R, Brummer T. Gene Expr Patterns. 2014 Jul;15(2):124-34na.2014.00145 10.1016/j.gep.2014.05.005
Extensive postzygotic mosaicism for a novel keratin 10 mutation in epidermolytic ichthyosis. Kiritsi D, Nanda A, Kohlhase J, Bernhard C, Bruckner-Tuderman L, Happle R, Has C. Acta Derm Venereol. 2014 May;94(3):346-8. 10.2340/00015555-1695
Functional architecture of an optic flow-responsive area that drives horizontal eye movements in zebrafish. Kubo F, Hablitzel B, Dal MM, Driever W, Baier H, Arrenberg AB Neuron 81: 1344-59. 10.1016/j.neuron.2014.02.043
Improving Detection of Deformable Objects in Volumetric Data D. Mai, J. Dürr, K. Palme, O. Ronneberger British Machine Vision Conference (BMVC), 2014
Interaction with the Bardet-Biedl gene product TRIM32/BBS11 modifies the half-life and localization of Glis2/NPHP7. Ramachandran H, Schäfer T, Kim Y, Herfurth K, Hoff S, Lienkamp SS, Kramer-Zucker A, Walz G J Biol Chem. 2014 Mar 21;289(12):8390-401. 10.1074/jbc.M113.534024
Molecular Heterogeneity of Epidermolysis Bullosa Simplex: Contribution of EXPH5 Mutations. Pigors M, Schwieger-Briel A, Leppert J, Kiritsi D, Kohlhase J,Bruckner-Tuderman L, Has C. J Invest Dermatol. 2014 Mar;134(3):842-5. 10.1038/jid.2013.373
N-glycosylation determines the abundance of the transient receptor potential channel TRPP2. Hofherr A, Wagner C, Fedeles S, Somlo S, Köttgen M. J Biol Chem. 2014 May 23;289(21):14854-67. 10.1074/jbc.M114.562264
nkx2.1 and nkx2.4 genes function partially redundant during development of the zebrafish hypothalamus, preoptic region, and pallidum. Manoli M, Driever W. Front Neuroanat. 2014 Dec 2;8:145 10.3389/fnana.2014.00145
Optical Flow Guided Cell Segmentation and Tracking in Developing Tissue K. Liu, S. Lienkamp, A. Shindo, J. Wallingford, G. Walz, O. Ronneberger IEEE International Symposium on Biomedical Imaging (ISBI): 298--301, 2014
P2X7-dependent, but differentially regulated release of IL-6, CCL2, and TNF-a in cultured mouse microglia. Shieh CH, Heinrich A, Serchov T, van Calker D, Biber K Glia. 2014 Apr;62(4):592-607. 10.1002/glia.22628
Pou5f1 protein expression and posttranslational modification during early zebrafish development. Lippok B, Song S, Driever W. Dev Dyn 243: 468-77. 10.1002/dvdy.24079
Pou5f1/Oct4 promotes cell survival via direct activation of mych expression during zebrafish gastrulation. Kotkamp K, Kur E, Wendik B, Polok BK, Ben-Dor S, Onichtchouk D, et al. PLoS One 9: e92356. 10.1371/journal.pone.0092356
Quantitative analysis of the mitochondrial and plastid proteomes of the moss Physcomitrella patens reveals protein macrocompartmentation and microcompartmentation. Mueller, S.J., D. Lang, S.N.W. Hoernstein, E.G.E. Lang, C. Schuessele, A. Schmidt, M. Fluck, D. Leisibach, C. Niegl, A.D. Zimmer, A. Schlosser, R. Reski Plant Physiol. 2014 Apr;164(4):2081-95 10.1104/pp.114.235754
RhoA activation by CNFy restores cell-cell adhesion in kindlin-2 deficient keratinocytes. He Y, Sonnenwald T, Sprenger A, Hansen U, Dengjel J, Bruckner-Tuderman L, Schmidt G, Has C. J Pathol. 2014 Jul;233(3):269-80. 10.1002/path.4350
Rotation-Invariant HOG Descriptors using Fourier Analysis in Polar and Spherical Coordinates K. Liu, H. Skibbe, T. Schmid, T. Blein, K. Palme, T. Brox, and O. Ronneberger Int J Computer Vision February 2014, Volume 106, Issue 3, pp 342-364
Signaling Switch of the Axon Guidance Receptor Robo3 during Vertebrate Evolution. Zelina P, Blockus H, Zagar Y, Peres A, Friocourt F, Wu Z, Rama N, Fouquet C, Hohenester E, Tessier-Lavigne M, Schweitzer J, Roest Crollius H, Chedotal A Neuron. 2014 Dec 17;84(6):1258-72. 10.1016/j.neuron.2014.11.004
Stochastic nanoroughness modulates neuron-astrocyte interactions and function via mechanosensing cation channels. Blumenthal NR, Hermanson O, Heimrich B, Shastri VP. Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16124-9. 10.1073/pnas.1412740111
The iRoCS Toolbox--3D analysis of the plant root apical meristem at cellular resolution. Schmidt T, Pasternak T, Aubry D, Dovzhenko A, Teale W, Burkhardt H, Ronneberger O, Palme K. Plant J. 2014 Mar;77(5):806-14 10.1111/tpj.12429
The irre Cell Recognition Module (IRM) Protein Kirre Is Required to Form the Reciprocal Synaptic Network of L4 Neurons in the Drosophila Lamina. Kevin Lüthy, Birgit Ahrens, Shilpa Rawal, Zhiyuan Lu, Dorota Tarnogorska, Ian A Meinertzhagen, Karl-Friedrich Fischbach J Neurogenet. 2014 Sep-Dec;28(3-4):291-301. 10.3109/01677063.2014.883390
The Missense Mutation p.R1303Q in Type XVII Collagen Underlies Junctional Epidermolysis Bullosa Resembling Kindler Syndrome. Has C, Kiritsi D, Mellerio JE, Franzke CW, Wedgeworth E, Tantcheva-Poor I, Kernland-Lang K, Itin P, Simpson MA, Dopping-Hepenstal PJ, Fujimoto W, McGrath JA, Bruckner-Tuderman L. J Invest Dermatol. 2014 Mar;134(3):845-9. 10.1038/jid.2013.367
TNAP activity is localized at critical sites of retinal neurotransmission across various vertebrate species. Kántor O, Varga A, Kovács-Öller T, Énzsöly A, Balogh L, Baksa G, Szepessy Z, Fonta C, Roe AW, Nitschke R, Szél Á, Négyessy L, Völgyi B, Lukáts Á. Cell Tissue Res. 2014 Oct;358(1):85-98. 10.1007/s00441-014-1944-3
Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling. Löffek S, Hurskainen T, Jackow J, Sigloch FC, Schilling O, Tasanen K, Bruckner-Tuderman L, Franzke CW. PLoS One. 2014 Feb 5;9(2):e87263. 10.1371/journal.pone.0087263
Validation of Micro-CT/FMT Multimodal in vivo Imaging in Rat D. Vonwill, J. Chistensen, S. Fischer, O. Ronneberger, and V.P. Shastri Mol Imaging Biol. 2014 Jun;16(3):350-61 10.1007/s11307-013-0698-8

2013

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Novel and recurrent /AAGAB/ mutations: clinical variability and molecular consequences. Kiritsi D, Chmel N, Arnold AW, Jakob T, Bruckner-Tuderman L, Has C. J Invest Dermatol. 2013 Oct;133(10):2483-6. 10.1038/jid.2013.171
vglut2 and gad expression reveal distinct patterns of dual GABAergic versus glutamatergic cotransmitter phenotypes of dopaminergic and noradrenergic neurons in the zebrafish brain. Filippi A, Mueller T, Driever W. J Comp Neurol 522: 2019-37. 10.1002/cne.23524
A complex of BBS1 and NPHP7 is required for cilia motility in zebrafish. Kim YH, Epting D, Slanchev K, Engel C, Walz G, Kramer-Zucker A PLoS One. 2013 Sep 12;8(9):e72549 10.1371/journal.pone.0072549
A mutation in cnot8, component of the Ccr4-not complex regulating transcript stability, affects expression levels of developmental regulators and reveals a role of Fgf3 in development of caudal hypothalamic dopaminergic neurons. Koch P, Lohr HB, Driever W PLoS One 9: e113829. 10.1371/journal.pone.0113829
A novel domain regulating degradation of the glomerular slit diaphragm protein podocin in cell culture systems. Gödel M, Ostendorf BN, Baumer J, Weber K, Huber TB. PLoS One. 2013;8(2):e57078. 10.1371/journal.pone.0057078
ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3 Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstädter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS Nat Genet. 2013 Aug;45(8):951-6. 10.1038/ng.2681
aPKC?/? and aPKC? contribute to podocyte differentiation and glomerular maturation. Hartleben B, Widmeier E, Suhm M, Worthmann K, Schell C, Helmstädter M, Wiech T, Walz G, Leitges M, Schiffer M, Huber TB. J Am Soc Nephrol. 2013 Feb;24(2):253-67. 10.1681/ASN.2012060582
Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK. Geissler, A., Haun, F., Frank, D., Wieland, K., Simon, M., Idzko, M., Davis, R., Maurer, U. & Borner, C. Cell Death Differ. (2013) 20, 1317–1329 10.1038/cdd.2013.78
Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling. Schober A, Parlato R, Huber K, Kinscherf R, Hartleben B, Huber TB, Schütz G, Unsicker K. J Neuroendocrinol. 2013 Jan;25(1):34-47. 10.1111/j.1365-2826.2012.02367.x
Collagen VII plays a dual role in wound healing. Nyström A, Velati D, Mittapalli VR, Fritsch A, Kern JS, Bruckner-Tuderman L. J Clin Invest. 2013 Aug;123(8):3498-509. 10.1172/JCI68127
Discriminative Detection and Alignment in Volumetric Data Dominic Mai, Philipp Fischer, Thomas Blein, Jasmin Dürr, Klaus Palme, Thomas Brox, Olaf Ronneberger Pattern Recognition Lecture Notes in Computer Science Volume 8142, 2013, pp 205-214
Enlightening the brain: linking deep brain photoreception with behavior and physiology. Fernandes AM, Fero K, Driever W, Burgess HA Bioessays 35: 775-9. 10.1002/bies.201300034
Epidermolysis bullosa simplex ogna revisited. Kiritsi D, Pigors M, Tantcheva-Poor I, Wessel C, Arin MJ, Kohlhase J, Bruckner-Tuderman L, Has C. J Invest Dermatol. 2013 Jan;133(1):270-3. 10.1038/jid.2012.248
Functional and structural MRI biomarkers to detect pre-clinical neurodegeneration. Abdulkadir A, Ronneberger O, Wolf RC, Pfleiderer B, Saft C, Klöppel S. Curr Alzheimer Res. 2013 Feb;10(2):125-34. 10.2174/1567205011310020002
Global remodelling of cellular microenvironment due to loss of collagen VII. Küttner V, Mack C, Rigbolt KT, Kern JS, Schilling O, Busch H, Bruckner-Tuderman L, Dengjel J. Mol Syst Biol. 2013 Apr 16;9:657. 10.1038/msb.2013.17
Hydrogen Sulfide Prevents Hyperoxia-induced Lung Injury by Downregulating Reactive Oxygen Species Formation and Angiopoietin-2 Release. Faller S, Spassov SG, Zimmermann KK, Ryter SW, Buerkle H, Loop T, Schmidt R, Strosing KM, Hoetzel A. Curr Pharm Des. 2013;19(15):2715-21 10.2174/1381612811319150006
Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling. Weber M, Gawanbacht A, Habjan M, Rang A, Borner C, Schmidt AM, Veitinger S, Jacob R, Devignot S, Kochs G, García-Sastre A, Weber F. Cell Host Microbe. 2013 Mar 13;13(3):336-46. 10.1016/j.chom.2013.01.012
Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells. Thedieck K, Holzwarth B, Prentzell MT, Boehlke C, Kläsener K, Ruf S, Sonntag AG, Maerz L, Grellscheid SN, Kremmer E, Nitschke R, Kuehn EW, Jonker JW, Groen AK, Reth M, Hall MN, Baumeister R. Cell. 2013 Aug 15;154(4):859-74. 10.1016/j.cell.2013.07.031
Integrating anatomy and function for zebrafish circuit analysis. Frontiers in Neural Circuit Analysis 7 Driever, W. and Arrenberg A.B. Front Neural Circuits. 2013 Apr 23;7:74. 10.3389/fncir.2013.00074
Joint 3D Cell Segmentation and Classification in the Arabidopsis Root using Energy Minimization and Shape Priors K. Liu, T. Schmidt, T. Blein, J. Dürr, K. Palme, O. Ronneberger IEEE International Symposium on Biomedical Imaging (ISBI): 422--425, 2013
Kidins220/ARMS Associates with B-Raf and the TCR,Promoting Sustained Erk Signaling in T Cells Sumit Deswal, Anja Meyer, Gina J. Fiala, Anja E. Eisenhardt, Lisa C. Schmitt, Mogjiborahman Salek, Tilman Brummer, Oreste Acuto and Wolfgang W. A. Schamel J Immunol. 2013 Mar 1;190(5):1927-35. 10.4049/jimmunol.1200653
Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells. Boehlke Christopher, Kotsis Fruzsina, Buchholz Bjoern, Powelske Christian, Eckardt Kai-Uwe, Walz , Nitschke Roland, Kuehn E. Wolfgang. PLoS One. 2013 May 1;8(5):e62165. 10.1371/journal.pone.0062165
Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth. Schmid B, Hruscha A, Hogl S, Banzhaf-Strathmann J, Strecker K, van der Zee J, Teucke M, Eimer S, Hegermann J, Kittelmann M, Kremmer E, Cruts M, Solchenberger B, Hasenkamp L, van Bebber F, Van Broeckhoven C, Edbauer D, Lichtenthaler SF, Haass C. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):4986-91 10.1073/pnas.1218311110
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways. Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Hölscher C, Müller DN, Luckow B, Brocker T, Debowski K, Fritz G, Opdenakker G, Diefenbach A, Biber K, Heikenwalder M, Geissmann F, Rosenbauer F, Prinz M. Nat Neurosci. 2013 Mar;16(3):273-80. 10.1038/nn.3318
Molecular evolution of myelin basic protein, an abundant structural myelin component. Nawaz S, Schweitzer J, Jahn O, Werner HB Glia. 2013 Aug;61(8):1364-77. 10.1002/glia.22520
Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks. Boerries M, Grahammer F, Eiselein S, Buck M, Meyer C, Goedel M, Bechtel W, Zschiedrich S, Pfeifer D, Laloë D, Arrondel C, Gonçalves S, Krüger M, Harvey SJ, Busch H, Dengjel J, Huber TB. Kidney Int. 2013 Jan 30.
Molecular understanding of the slit diaphragm. Grahammer F, Schell C, Huber TB. Pediatr Nephrol. 2013 Oct;28(10):1957-62. 10.1038/ki.2012.487
Non-canonical function of Bax in stress-induced nuclear protein redistribution. Lindenboim L, Ferrando-May E, Borner C, Stein R. Cell Mol Life Sci. 2013 Mar 9.
Non-directional radial intercalation dominates deep cell behavior during zebrafish epiboly. Bensch R, Song S, Ronneberger O, Driever W Biol Open 2: 845-54. 10.1242/bio.20134614
N-WASP Is Required for Stabilization of Podocyte Foot Processes. Schell C, Baumhakl L, Salou S, Conzelmann AC, Meyer C, Helmstädter M, Wrede C, Grahammer F, Eimer S, Kerjaschki D, Walz G, Snapper S, Huber TB. J Am Soc Nephrol. 2013 Mar 7. 10.1681/ASN.2012080844
Orthopedia transcription factor otpa and otpb paralogous genes function during dopaminergic and neuroendocrine cell specification in larval zebrafish. Fernandes AM, Beddows E, Filippi A, Driever W PLoS One 8: e75002. doi: 10.1371 10.1371/journal.pone.0075002
Plastid-localized glutathione reductase2-regulated glutathione redox status is essential for Arabidopsis root apical meristem maintenance. Yu X, Pasternak T, Eiblmeier M, Ditengou F, Kochersperger P, Sun J, Wang H, Rennenberg H, Teale W, Paponov I, Zhou W, Li C, Li X, Palme K. Plant Cell. 2013 Nov;25(11):4451-68. 10.1105/tpc.113.117028
Pou5f1-dependent EGF expression controls E-cadherin endocytosis, cell adhesion, and zebrafish epiboly movements. Song S, Eckerle S, Onichtchouk D, Marrs JA, Nitschke R, Driever W. Dev Cell. 2013 Mar 11;24(5):486-501 10.1016/j.devcel.2013.01.016
Reelin induces EphB activation. Bouché E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH. Cell Res. 2013 Apr;23(4):473-90. 10.1038/cr.2013.7
Regulation in Nephrotic Syndrome Amelie T. van der Ven,1 Jillian K. Warejko,1 Ankana Daga,1 Eugen Widmeier,1 Zebrafish 10: 401-21. 10.1089/zeb.2013.0886
Root gravitropism and root hair development constitute coupled developmental responses regulated by auxin homeostasis in the Arabidopsis root apex. Rigas S, Ditengou FA, Ljung K, Daras G, Tietz O, Palme K, Hatzopoulos P. New Phytol. 2013 Mar;197(4):1130-41. 10.1111/nph.12092
Semi-automatic determination of cell surface areas used in systems biology. Morath V, Keuper M, Rodriguez-Franco M, Deswal S, Fiala G, Blumenthal B, Kaschek D, Timmer J, Neuhaus G, Ehl S, Ronneberger O, Schamel WW. Front Biosci (Elite Ed). 2013 Jan 1;5:533-45. 10.2741/e635
Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Schweitzer J, Löhr H, Bonkowsky JL, Hübscher K, Driever W. Development. 2013 Jan 1;140(1):93-106. 10.1242/dev.087825
Surveillance-Activated Defenses Block the ROS-Induced Mitochondrial Unfolded Protein Response. Runkel ED, Liu S, Baumeister R, Schulze E. PLoS Genet. 2013 Mar;9(3):e1003346. 10.1371/journal.pgen.1003346
The Arabidopsis thaliana Mob1A gene is required for organ growth and correct tissue patterning of the root tip. Pinosa F, Begheldo M, Pasternak T, Zermiani M, Paponov IA, Dovzhenko A, Barcaccia G, Ruperti B, Palme K. Ann Bot. 2013 Dec;112(9):1803-14. 10.1093/aob/mct235
The Drosophila BMPRII, wishful thinking, is required for eggshell patterning. Marmion RA., Jevtic M., Springhorn A., Pyrowolakis G., Yakoby N. Dev Biol. 2013 Mar 1;375(1):45-53 10.1016/j.ydbio.2012.12.011
The Podocyte Slit Diaphragm – from a thin grey line to a complex signalling hub. Grahammer F, Schell C, Huber TB Nat Rev Nephrol. 2013 Oct;9(10):587-98. 10.1038/nrneph.2013.169
TNFa-induced lysosomal membrane permeability (LMP) is downstream of MOMP and triggered by caspase-mediated p75 cleavage and ROS formation Huai, J., Vögtle, F.-N., Jöckel, L., Li, Y., Kiefer, T. Ricci, J.-E. & Borner, C. J Cell Sci. 2013 Sep 1;126(Pt 17):4015-25 10.1242/jcs.129999
TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development. Ruf V, Holzem C, Peyman T, Walz G, Blackwell TK, Neumann-Haefelin E Dev Biol. 2013 Dec 15;384(2):214-27. 10.1016/j.ydbio.2013.08.011
Variational Attenuation Correction in Two-View Confocal Microscopy Schmidt T, Dürr J, Keuper M, Blein T, Palme K, Ronneberger O BMC Bioinformatics. 2013 Dec 18;14:366. 10.1186/1471-2105-14-366
Vps34 Deficiency Reveals the Importance of Endocytosis for Podocyte Homeostasis. Bechtel W, Helmstädter M, Balica J, Hartleben B, Kiefer B, Hrnjic F, Schell C, Kretz O, Liu S, Geist F, Kerjaschki D, Walz G, Huber TB. J Am Soc Nephrol. 2013 Mar 19. 10.1681/ASN.2012070700
Zebrafish collagen XIV is transiently expressed in epithelia and is required for proper function of certain basement membranes. Bader HL, Lambert E, Guiraud A, Malbouyres M, Driever W, Koch M, Ruggiero F. J Biol Chem. 2013 Mar 8;288(10):6777-87. 10.1074/jbc.M112.430637

2012

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A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation. Dalle Pezze P, Sonntag AG, Thien A, Prentzell MT, Gödel M, Fischer S, Neumann-Haefelin E, Huber TB, Baumeister R, Shanley DP, Thedieck K. Sci Signal. 2012 Mar 27;5(217):ra25. 10.1126/scisignal.2002469
Analysis of transcriptional codes for zebrafish dopaminergic neurons reveals essential functions of Arx and Isl1 in prethalamic dopaminergic neuron development. Filippi A, Jainok C, Driever W. Dev Biol. 2012 Sep 1;369(1):133-49. 10.1016/j.ydbio.2012.06.010
Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury. Liu S, Hartleben B, Kretz O, Wiech T, Igarashi P, Mizushima N, Walz G, Huber TB. Autophagy. 2012 May 1;8(5):826-37. 10.4161/auto.19419
BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons. Dieni S, Matsumoto T, Dekkers M, Rauskolb S, Ionescu MS, Deogracias R, Gundelfinger ED, Kojima M, Nestel S, Frotscher M, Barde YA. J Cell Biol. 2012 Mar 19;196(6):775-88. 10.1083/jcb.201201038
CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Panizzi JR, Becker-Heck A, Castleman VH, Al-Mutairi DA, Liu Y, Loges NT, Pathak N, Austin-Tse C, Sheridan E, Schmidts M, Olbrich H, Werner C, Häffner K, Hellman N, Chodhari R, Gupta A, Kramer-Zucker A, Olale F, Burdine RD, Schier AF, O'Callaghan C, Chung EM, Reinhardt R, Mitchison HM, King SM, Omran H, Drummond IA. Nat Genet. 2012 May 13;44(6):714-9. 10.1038/ng.2277
Cholesterol and sphingomyelin drive ligand-independent T-cell antigen receptor nanoclustering. Molnár E, Swamy M, Holzer M, Beck-García K, Worch R, Thiele C, Guigas G, Boye K, Luescher IF, Schwille P, Schubert R, Schamel WW J Biol Chem. 2012 Dec 14;287(51):42664-74. doi: 10.1074/jbc.M112.386045. 10.1074/jbc.m112.386045
Clonal relationship between langerhans cell histiocytosis and myeloid sarcoma. Schmitt-Graeff AH, Duerkop H, Vollmer-Kary B, Haxelmans S, Nitschke R, Fisch P, Germing U, Stein H. Leukemia. 2012 Jul;26(7):1707-10. 10.1038/leu.2012.27
Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly. Owald D, Khorramshahi O, Gupta VK, Banovic D, Depner H, Fouquet W, Wichmann C, Mertel S, Eimer S, Reynolds E, Holt M, Aberle H, Sigrist SJ. Nat Neurosci. 2012 Sep;15(9):1219-26. 10.1038/nn.3183
Deep brain photoreceptors control light-seeking behavior in zebrafish larvae. Fernandes AM, Fero K, Arrenberg AB, Bergeron SA, Driever W, Burgess HA. Curr Biol. 2012 Nov 6;22(21):2042-7. 10.1016/j.cub.2012.08.016
Dopaminergic and noradrenergic circuit development in zebrafish. Schweitzer J, Lohr H, Filippi A, Driever W. Dev Neurobiol. 2012 Mar;72(3):256-68. 10.1002/dneu.20911
Emerging role of autophagy in kidney function, diseases and aging. Huber TB, Edelstein CL, Hartleben B, Inoki K, Dong Z, Koya D, Kume S, Lieberthal W, Pallet N, Quiroga A, Ravichandran K, Susztak K, Yoshida S, Dong Z. Autophagy. 2012 Jul 1;8(7):1009-31. 10.4161/auto.19821
Experimental epilepsy affects Notch1 signalling and the stem cell pool in the dentate gyrus. Sibbe M, Häussler U, Dieni S, Althof D, Haas CA, Frotscher M. Eur J Neurosci. 2012 Dec;36(12):3643-52 10.1111/j.1460-9568.2012.08279.x
FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair. Zhou W, Otto EA, Cluckey A, Airik R, Hurd TW, Chaki M, Diaz K, Lach FP, Bennett GR, Gee HY, Ghosh AK, Natarajan S, Thongthip S, Veturi U, Allen SJ, Janssen S, Ramaswami G, Dixon J, Burkhalter F, Spoendlin M, Moch H, Mihatsch MJ, Verine J, Reade R, Soliman H, Godin M, Kiss D, Monga G, Mazzucco G, Amann K, Artunc F, Newland RC, Wiech T, Zschiedrich S, Huber TB, Friedl A, Slaats GG, Joles JA, Goldschmeding R, Washburn J, Giles RH, Levy S, Smogorzewska A, Hildebrandt F. Nat Genet. 2012 Jul 8;44(8):910-5 10.1038/ng.2347
Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencing. Voz ML, Coppieters W, Manfroid I, Baudhuin A, Von Berg V, Charlier C, Meyer D, Driever W, Martial JA, Peers B. PLoS One. 2012;7(4):e34671. 10.1371/journal.pone.0034671
Fast rotation invariant 3D feature computation utilizing efficient local neighborhood operators. Skibbe H, Reisert M, Schmidt T, Brox T, Ronneberger O, Burkhardt H. IEEE Trans Pattern Anal Mach Intell. 2012 Aug;34(8):1563-75. 10.1109/tpami.2011.263
Fluorescence-activated cell sorting (FACS) of fluorescently tagged cells from zebrafish larvae for RNA isolation. Manoli M, Driever W Cold Spring Harb Protoc 2012. 10.1101/pdb.prot069633
Functional study of mammalian Neph proteins in Drosophila melanogaster. Helmstädter M, Lüthy K, Gödel M, Simons M, Ashish, Nihalani D, Rensing SA, Fischbach KF, Huber TB. PLoS One. 2012;7(7):e40300. 10.1371/journal.pone.0040300
Genetically controlled upregulation of adenosine A(1) receptor expression enhances the survival of primary cortical neurons. Serchov T, Atas HC, Normann C, van Calker D, Biber K. Mol Neurobiol. 2012 Oct;46(2):535-44. 10.1007/s12035-012-8321-6
Guidelines for the use and interpretation of assays for monitoring autophagy. Klionsky DJ, ..., Huber TB, ..., Zuckerbraun B Autophagy. 2012 Apr;8(4):445-544. 10.4161/auto.19496
High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Schwenk J, Harmel N, Brechet A, Zolles G, Berkefeld H, Müller CS, Bildl W, Baehrens D, Hüber B, Kulik A, Klöcker N, Schulte U, Fakler B. Neuron. 2012 May 24;74(4):621-33. 10.1016/j.neuron.2012.03.034
How many ways can a podocyte die? Tharaux PL, Huber TB. Semin Nephrol. 2012 Jul;32(4):394-404. 10.1016/j.semnephrol.2012.06.011
Influence of cell-to-cell variability on spatial pattern formation. Greese B, Wester K, Bensch R, Ronneberger O, Timmer J, Huulskamp M, Fleck C. IET Syst Biol. 2012 Aug;6(4):143-53. 10.1049/iet-syb.2011.0050
Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity. Fatouros C, Pir GJ, Biernat J, Koushika SP, Mandelkow E, Mandelkow EM, Schmidt E, Baumeister R. Hum Mol Genet. 2012 Aug 15;21(16):3587-603. 10.1093/hmg/dds190
Integrin a3 mutations with kidney, lung, and skin disease. Has C, Spartà G, Kiritsi D, Weibel L, Moeller A, Vega-Warner V, Waters A, He Y, Anikster Y, Esser P, Straub BK, Hausser I, Bockenhauer D, Dekel B, Hildebrandt F, Bruckner-Tuderman L, Laube GF. N Engl J Med. 2012 Apr 19;366(16):1508-14. 10.1056/nejmoa1110813
Is podocyte research at a tipping point? Report from the 9(th) International Podocyte Conference. Schell CB, Kerjaschki D, Reiser J, Huber TB. Kidney Int. 2012 Nov;82(10):1041-3. 10.1038/ki.2012.319
Mammalian target of rapamycin signaling in the podocyte. Inoki K, Huber TB. Curr Opin Nephrol Hypertens. 2012 May;21(3):251-7. 10.1097/mnh.0b013e3283520f38
Multiview deblurring for 3-D images from light-sheet-based fluorescence microscopy. Temerinac-Ott M, Ronneberger O, Ochs P, Driever W, Brox T, Burkhardt H. IEEE Trans Image Process. 2012 Apr;21(4):1863-73. 10.1109/tip.2011.2181528
Neuroprotective function for ramified microglia in hippocampal excitotoxicity. Vinet J, Weering HR, Heinrich A, Kälin RE, Wegner A, Brouwer N, Heppner FL, Rooijen Nv, Boddeke HW, Biber K. J Neuroinflammation. 2012 Jan 31;9:27. 10.1186/1742-2094-9-27
New players in the pathogenesis of focal segmental glomerulosclerosis. Schell C, Huber TB. Nephrol Dial Transplant. 2012 Sep;27(9):3406-12. 10.1093/ndt/gfs273
Novel roles of Caenorhabditis elegans heterochromatin protein HP1 and linker histone in the regulation of innate immune gene expression. Studencka M, Konzer A, Moneron G, Wenzel D, Opitz L, Salinas-Riester G, Bedet C, Krüger M, Hell SW, Wisniewski JR, Schmidt H, Palladino F, Schulze E, Jedrusik-Bode M. Mol Cell Biol. 2012 Jan;32(2):251-65. 10.1128/mcb.05229-11
Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter. Chua JJ, Butkevich E, Worseck JM, Kittelmann M, Grønborg M, Behrmann E, Stelzl U, Pavlos NJ, Lalowski MM, Eimer S, Wanker EE, Klopfenstein DR, Jahn R. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5862-7. 10.1073/pnas.1113819109
PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans. Grall A, Guaguère E, Planchais S, Grond S, Bourrat E, Hausser I, Hitte C, Le Gallo M, Derbois C, Kim GJ, Lagoutte L, Degorce-Rubiales F, Radner FP, Thomas A, Küry S, Bensignor E, Fontaine J, Pin D, Zimmermann R, Zechner R, Lathrop M, Galibert F, André C, Fischer J. Nat Genet. 2012 Jan 15;44(2):140-7. 10.1038/ng.1056
RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate. Shi A, Liu O, Koenig S, Banerjee R, Chen CC, Eimer S, Grant BD. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2306-15. 10.1073/pnas.1205278109
RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans. Sasidharan N, Sumakovic M, Hannemann M, Hegermann J, Liewald JF, Olendrowitz C, Koenig S, Grant BD, Rizzoli SO, Gottschalk A, Eimer S. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18944-9. 10.1073/pnas.1203306109
Revertant mosaicism in a human skin fragility disorder results from slipped mispairing and mitotic recombination. Kiritsi D, He Y, Pasmooij AM, Onder M, Happle R, Jonkman MF, Bruckner-Tuderman L, Has C. J Clin Invest. 2012 May 1;122(5):1742-6. 10.1172/jci61976
Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury. Linkermann A, Bräsen JH, Himmerkus N, Liu S, Huber TB, Kunzendorf U, Krautwald S. Kidney Int. 2012 Apr;81(8):751-61. 10.1038/ki.2011.450
Role of L1CAM for axon sprouting and branching. Schäfer MK, Frotscher M. Cell Tissue Res. 2012 Jul;349(1):39-48. 10.1007/s00441-012-1345-4
Role of the polarity protein Scribble for podocyte differentiation and maintenance. Hartleben B, Widmeier E, Wanner N, Schmidts M, Kim ST, Schneider L, Mayer B, Kerjaschki D, Miner JH, Walz G, Huber TB. PLoS One. 2012;7(5):e36705. 10.1371/journal.pone.0036705
Shroom3 is required downstream of FGF signalling to mediate proneuromast assembly in zebrafish. Ernst S, Liu K, Agarwala S, Moratscheck N, Avci ME, Dalle Nogare D, Chitnis AB, Ronneberger O, Lecaudey V. Development. 2012 Dec;139(24):4571-81 10.1242/dev.083253
Sox9 and Sox8 are required for basal lamina integrity of testis cords and for suppression of FOXL2 during embryonic testis development in mice. Georg I, Barrionuevo F, Wiech T, Scherer G. Biol Reprod. 2012 Oct 25;87(4):99. 10.1095/biolreprod.112.101907
TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans. Hannemann M, Sasidharan N, Hegermann J, Kutscher LM, Koenig S, Eimer S. PLoS Genet. 2012;8(5):e1002722. 10.1371/journal.pgen.1002722
Temperature- and touch-sensitive neurons couple CNG and TRPV channel activities to control heat avoidance in Caenorhabditis elegans. Liu S, Schulze E, Baumeister R. PLoS One. 2012;7(3):e32360. 10.1371/journal.pone.0032360
TGM5 mutations impact epidermal differentiation in acral peeling skin syndrome. Pigors M, Kiritsi D, Cobzaru C, Schwieger-Briel A, Suárez J, Faletra F, Aho H, Mäkelä L, Kern JS, Bruckner-Tuderman L, Has C. J Invest Dermatol. 2012 Oct;132(10):2422-9. 10.1038/jid.2012.166
The endoplasmic reticulum localized PIN8 is a pollen-specific auxin carrier involved in intracellular auxin homeostasis. Dal Bosco C, Dovzhenko A, Liu X, Woerner N, Rensch T, Eismann M, Eimer S, Hegermann J, Paponov IA, Ruperti B, Heberle-Bors E, Touraev A, Cohen JD, Palme K. Plant J. 2012 Sep;71(5):860-70. 10.1111/j.1365-313x.2012.05037.x
The relevance of compartmentation for cysteine synthesis in phototrophic organisms. Birke H, Müller SJ, Rother M, Zimmer AD, Hoernstein SN, Wesenberg D, Wirtz M, Krauss GJ, Reski R, Hell R. Protoplasma. 2012 Jun;249 Suppl 2:S147-55 10.1007/s00709-012-0411-9
Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension. Lienkamp SS, Liu K, Karner CM, Carroll TJ, Ronneberger O, Wallingford JB, Walz G. Nat Genet. 2012 Dec;44(12):1382-7. 10.1038/ng.2452
ViBE-Z: a framework for 3D virtual colocalization analysis in zebrafish larval brains. Ronneberger O, Liu K, Rath M, Rueß D, Mueller T, Skibbe H, Drayer B, Schmidt T, Filippi A, Nitschke R, Brox T, Burkhardt H, Driever W. Nat Methods. 2012 Jun 17;9(7):735-42. 10.1038/nmeth.2076

2011

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DOI

A comparison of different automated methods for the detection of white matter lesions in MRI data. Klöppel S, Abdulkadir A, Hadjidemetriou S, Issleib S, Frings L, Thanh TN, Mader I, Teipel SJ, Hüll M, Ronneberger O. Neuroimage. 2011 Jul 15;57(2):416-22. 10.1016/j.neuroimage.2011.04.053
A novel MCF-10A line allowing conditional oncogene expression in 3D culture. Herr R, Wöhrle FU, Danke C, Berens C, Brummer T. Cell Commun Signal. 2011 Jul 13;9:17. 10.1186/1478-811x-9-17
CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs. Merveille AC, Davis EE, Becker-Heck A, Legendre M, Amirav I, Bataille G, Belmont J, Beydon N, Billen F, Clément A, Clercx C, Coste A, Crosbie R, de Blic J, Deleuze S, Duquesnoy P, Escalier D, Escudier E, Fliegauf M, Horvath J, Hill K, Jorissen M, Just J, Kispert A, Lathrop M, Loges NT, Marthin JK, Momozawa Y, Montantin G, Nielsen KG, Olbrich H, Papon JF, Rayet I, Roger G, Schmidts M, Tenreiro H, Towbin JA, Zelenika D, Zentgraf H, Georges M, Lequarré AS, Katsanis N, Omran H, Amselem S. Nat Genet. 2011 Jan;43(1):72-8. 10.1038/ng.726
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival. Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, Reinheckel T, Gu C, Huber TB, Ju W, Bitzer M, Rastaldi MP, Ruiz P, Tryggvason K, Shaw AS, Faul C, Sever S, Reiser J. J Clin Invest. 2011 Oct;121(10):3965-80. 10.1172/jci58552
Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems. Tay TL, Ronneberger O, Ryu S, Nitschke R, Driever W. Nat Commun. 2011 Jan 25;2:171. 10.1038/ncomms1171
Dpp signaling activity requires Pentagone to scale with tissue size in the growing Drosophila wing imaginal disc. Hamaratoglu F, de Lachapelle AM, Pyrowolakis G, Bergmann S, Affolter M. PLoS Biol. 2011 Oct;9(10):e1001182. 10.1371/journal.pbio.1001182
Drosophila sperm swim backwards in the female reproductive tract and are activated via TRPP2 ion channels. Köttgen M, Hofherr A, Li W, Chu K, Cook S, Montell C, Watnick T. PLoS One. 2011;6(5):e20031. 10.1371/journal.pone.0020031
Dynamic interactions of epidermal collagen XVII with the extracellular matrix: laminin 332 as a major binding partner. Nishie W, Kiritsi D, Nyström A, Hofmann SC, Bruckner-Tuderman L. Am J Pathol. 2011 Aug;179(2):829-37. 10.1016/j.ajpath.2011.04.019
Epileptiform activity interferes with proteolytic processing of Reelin required for dentate granule cell positioning. Tinnes S, Schäfer MK, Flubacher A, Münzner G, Frotscher M, Haas CA. FASEB J. 2011 Mar;25(3):1002-13. 10.1096/fj.10-168294
Expansion-repression mechanism for scaling the Dpp activation gradient in Drosophila wing imaginal discs. Ben-Zvi D, Pyrowolakis G, Barkai N, Shilo BZ. Curr Biol. 2011 Aug 23;21(16):1391-6. 10.1016/j.cub.2011.07.015
Fibroblast growth factor 2 regulates astrocyte differentiation in a region-specific manner in the hindbrain. Irmady K, Zechel S, Unsicker K. Glia. 2011 May;59(5):708-19. 10.1002/glia.21141
Fibroblast growth factor-2 deficiency causes defects in adult hippocampal neurogenesis, which are not rescued by exogenous fibroblast growth factor-2. Werner S, Unsicker K, von Bohlen und Halbach O. J Neurosci Res. 2011 Oct;89(10):1605-17. 10.1002/jnr.22680
F-spondin regulates neuronal survival through activation of disabled-1 in the chicken ciliary ganglion. Peterziel H, Sackmann T, Strelau J, Kuhn PH, Lichtenthaler SF, Marom K, Klar A, Unsicker K. Mol Cell Neurosci. 2011 Feb;46(2):483-97 10.1016/j.mcn.2010.12.001
Full-length L1CAM and not its ?2?27 splice variant promotes metastasis through induction of gelatinase expression. Hauser S, Bickel L, Weinspach D, Gerg M, Schäfer MK, Pfeifer M, Hazin J, Schelter F, Weidle UH, Ramser J, Volkmann J, Meindl A, Schmitt M, Schrötzlmair F, Altevogt P, Krüger A. PLoS One. 2011 Apr 25;6(4):e18989. 10.1371/journal.pone.0018989
Functional and spatial analysis of C. elegans SYG-1 and SYG-2, orthologs of the Neph/nephrin cell adhesion module directing selective synaptogenesis. Wanner N, Noutsou F, Baumeister R, Walz G, Huber TB, Neumann-Haefelin E. PLoS One. 2011;6(8):e23598. 10.1371/journal.pone.0023598
GSK3ß inactivation in podocytes results in decreased phosphorylation of p70S6K accompanied by cytoskeletal rearrangements and inhibited motility. George B, Vollenbröker B, Saleem MA, Huber TB, Pavenstädt H, Weide T. Am J Physiol Renal Physiol. 2011 May;300(5):F1152-62. 10.1152/ajprenal.00373.2010
Highly photoluminescent and photostable CdSe quantum dot–nylon hybrid composites for efficient light conversion applications, Yuan,Y., Riehle,F., Nitschke,R., Krüger, M. Materials Science and Engineering B 177 (2011), 245 -250. 10.1016/j.mseb.2011.12.003
High-resolution permanent photoresist laminate TMMF for sealed microfluidic structures in biological applications N Wangler, L Gutzweiler, K Kalkandjiev, C Müller, F Mayenfels, H Reinecke, R Zengerle, N Paust J. Micromech. Microeng. 21 095009 doi:10.1088/0960-1317/21/9/095009 10.1088/0960-1317/21/9/095009
Implications of autophagy for glomerular aging and disease. Weide T, Huber TB. Cell Tissue Res. 2011 Mar;343(3):467-73. 10.1007/s00441-010-1115-0
Kindler syndrome: extension of FERMT1 mutational spectrum and natural history. Has C, Castiglia D, del Rio M, Diez MG, Piccinni E, Kiritsi D, Kohlhase J, Itin P, Martin L, Fischer J, Zambruno G, Bruckner-Tuderman L. Hum Mutat. 2011 Nov;32(11):1204-12. 10.1002/humu.21576
Kindlin-1 and -2 have overlapping functions in epithelial cells implications for phenotype modification. He Y, Esser P, Heinemann A, Bruckner-Tuderman L, Has C. Am J Pathol. 2011 Mar;178(3):975-82. 10.1016/j.ajpath.2010.11.053
Lack of plakoglobin leads to lethal congenital epidermolysis bullosa: a novel clinico-genetic entity. Pigors M, Kiritsi D, Krümpelmann S, Wagner N, He Y, Podda M, Kohlhase J, Hausser I, Bruckner-Tuderman L, Has C. Hum Mol Genet. 2011 May 1;20(9):1811-9. 10.1093/hmg/ddr064
mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression. Huber TB, Walz G, Kuehn EW. Kidney Int. 2011 Mar;79(5):502-11. 10.1038/ki.2010.457
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. Inoki K, Mori H, Wang J, Suzuki T, Hong S, Yoshida S, Blattner SM, Ikenoue T, Rüegg MA, Hall MN, Kwiatkowski DJ, Rastaldi MP, Huber TB, Kretzler M, Holzman LB, Wiggins RC, Guan KL. J Clin Invest. 2011 Jun;121(6):2181-96. 10.1172/jci44771
Nephrocystin-4 is required for pronephric duct-dependent cloaca formation in zebrafish. Slanchev K, Pütz M, Schmitt A, Kramer-Zucker A, Walz G. Hum Mol Genet. 2011 Aug 15;20(16):3119-28 10.1093/hmg/ddr214
Neurologic and ocular phenotype in Pitt-Hopkins syndrome and a zebrafish model. Brockschmidt A, Filippi A, Charbel Issa P, Nelles M, Urbach H, Eter N, Driever W, Weber RG. Hum Genet. 2011 Nov;130(5):645-55. 10.1007/s00439-011-0999-4
Nuclear localization and interaction with COP1 are required for STO/BBX24 function during photomorphogenesis. Yan H, Marquardt K, Indorf M, Jutt D, Kircher S, Neuhaus G, Rodríguez-Franco M. Plant Physiol. 2011 Aug;156(4):1772-82. 10.1104/pp.111.180208
Old friends form alliance against podocytes. Simons M, Huber TB. Kidney Int. 2011 Dec;80(11):1117-9. 10.1038/ki.2011.298
Photoconversion and nuclear trafficking cycles determine phytochrome A's response profile to far-red light. Rausenberger J, Tscheuschler A, Nordmeier W, Wüst F, Timmer J, Schäfer E, Fleck C, Hiltbrunner A. Cell. 2011 Sep 2;146(5):813-25. 10.1016/j.cell.2011.07.023
Pou5f1 contributes to dorsoventral patterning by positive regulation of vox and modulation of fgf8a expression. Belting HG, Wendik B, Lunde K, Leichsenring M, Mössner R, Driever W, Onichtchouk D. Dev Biol. 2011 Aug 15;356(2):323-36. 10.1016/j.ydbio.2011.05.660
Prorenin receptor is essential for podocyte autophagy and survival. Riediger F, Quack I, Qadri F, Hartleben B, Park JK, Potthoff SA, Sohn D, Sihn G, Rousselle A, Fokuhl V, Maschke U, Purfürst B, Schneider W, Rump LC, Luft FC, Dechend R, Bader M, Huber TB, Nguyen G, Muller DN. J Am Soc Nephrol. 2011 Dec;22(12):2193-202. 10.1681/asn.2011020200
Rapidly progressive hepatic alveolar echinococcosis in an ABO-incompatible renal transplant recipient. Geyer M, Wilpert J, Wiech T, Theilacker C, Stubanus M, Kramer-Zucker A, Fischer KG, Drognitz O, Frydrychowicz A, Kern W, Walz G, Pisarski P. Transpl Infect Dis. 2011 Jun;13(3):278-84. 10.1111/j.1399-3062.2010.00583.x
Regulation of GDF-15, a distant TGF-ß superfamily member, in a mouse model of cerebral ischemia. Schindowski K, von Bohlen und Halbach O, Strelau J, Ridder DA, Herrmann O, Schober A, Schwaninger M, Unsicker K. Cell Tissue Res. 2011 Feb;343(2):399-409. 10.1007/s00441-010-1090-5
Role for Reelin in neurotransmitter release. Hellwig S, Hack I, Kowalski J, Brunne B, Jarowyj J, Unger A, Bock HH, Junghans D, Frotscher M. J Neurosci. 2011 Feb 16;31(7):2352-60. d 10.1523/jneurosci.3984-10.2011
Role of kindlin-2 in fibroblast functions: implications for wound healing. He Y, Esser P, Schacht V, Bruckner-Tuderman L, Has C. J Invest Dermatol. 2011 Jan;131(1):245-56. 10.1038/jid.2010.273
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. Gödel M, Hartleben B, Herbach N, Liu S, Zschiedrich S, Lu S, Debreczeni-Mór A, Lindenmeyer MT, Rastaldi MP, Hartleben G, Wiech T, Fornoni A, Nelson RG, Kretzler M, Wanke R, Pavenstädt H, Kerjaschki D, Cohen CD, Hall MN, Rüegg MA, Inoki K, Walz G, Huber TB. J Clin Invest. 2011 Jun;121(6):2197-209. 10.1172/jci44774
Telomere shortening reduces Alzheimer's disease amyloid pathology in mice. Rolyan H, Scheffold A, Heinrich A, Begus-Nahrmann Y, Langkopf BH, Hölter SM, Vogt-Weisenhorn DM, Liss B, Wurst W, Lie DC, Thal DR, Biber K, Rudolph KL. Brain. 2011 Jul;134(Pt 7):2044-56. 10.1093/brain/awr133
TFG-1 function in protein secretion and oncogenesis. Witte K, Schuh AL, Hegermann J, Sarkeshik A, Mayers JR, Schwarze K, Yates JR 3rd, Eimer S, Audhya A. Nat Cell Biol. 2011 May;13(5):550-8. 10.1038/ncb2225
The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins. Höhne M, Lorscheider J, von Bardeleben A, Dufner M, Scharf MA, Gödel M, Helmstädter M, Schurek EM, Zank S, Gerke P, Kurschat C, Sivritas SH, Neumann-Haefelin E, Huber TB, Reinhardt HC, Schauss AC, Schermer B, Fischbach KF, Benzing T. Mol Cell Biol. 2011 Aug;31(16):3241-51. 10.1128/mcb.05286-11
The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. Luo L, Hannemann M, Koenig S, Hegermann J, Ailion M, Cho MK, Sasidharan N, Zweckstetter M, Rensing SA, Eimer S. Mol Biol Cell. 2011 Jul 15;22(14):2564-78. 10.1091/mbc.e10-06-0493
The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation. Becker-Heck A, Zohn IE, Okabe N, Pollock A, Lenhart KB, Sullivan-Brown J, McSheene J, Loges NT, Olbrich H, Haeffner K, Fliegauf M, Horvath J, Reinhardt R, Nielsen KG, Marthin JK, Baktai G, Anderson KV, Geisler R, Niswander L, Omran H, Burdine RD. Nat Genet. 2011 Jan;43(1):79-84. 10.1038/ng.727
The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates. Iwafuchi-Doi M, Yoshida Y, Onichtchouk D, Leichsenring M, Driever W, Takemoto T, Uchikawa M, Kamachi Y, Kondoh H. Dev Biol. 2011 Apr 15;352(2):354-66. 10.1016/j.ydbio.2010.12.027
The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Costello I, Pimeisl IM, Dräger S, Bikoff EK, Robertson EJ, Arnold SJ. Nat Cell Biol. 2011 Aug 7;13(9):1084-91. 10.1038/ncb2304
Transcriptional Interpretation of the EGFR Signaling Gradient. Fuchs A., Cheung LS. Charbonnier E., Shvartsman SY., Pyrowolakis G Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1572-7. doi: 10.1073/pnas.1115190109. Epub 2012 Jan 17. 10.1073/pnas.1115190109
Zona occludens proteins modulate podosome formation and function Kremerskothen J, Stölting M, Wiesner C, Korb-Pap A, van Vliet V, Linder S, Huber TB, Rottiers P, Reuzeau E, Genot E, Pavenstädt H. FASEB J. 2011 Feb;25(2):505-14. 10.1096/fj.10-155598

2010

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Journal

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A conserved activation element in BMP signaling during Drosophila development. Weiss A., Charbonnier E., Ellertsdóttir E., Wolf C., Schuh R., Pyrowolakis G.*, Affolter M.* (2010) *shared senior authorship Nat Struct Mol Biol. 2010 Jan;17(1):69-76. 10.1038/nsmb.1715
A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis. Neumann-Haefelin E, Kramer-Zucker A, Slanchev K, Hartleben B, Noutsou F, Martin K, Wanner N, Ritter A, Gödel M, Pagel P, Fu X, Müller A, Baumeister R, Walz G, Huber TB. Hum Mol Genet. 2010 Jun 15;19(12):2347-59. 10.1093/hmg/ddq108
Acral peeling skin syndrome with TGM5 gene mutations may resemble epidermolysis bullosa simplex in young individuals. Kiritsi D, Cosgarea I, Franzke CW, Schumann H, Oji V, Kohlhase J, Bruckner-Tuderman L, Has C J Invest Dermatol. 2010 Jun;130(6):1741-6. 10.1038/jid.2010.23
An integrative model for phytochrome B mediated photomorphogenesis: from protein dynamics to physiology. Rausenberger J, Hussong A, Kircher S, Kirchenbauer D, Timmer J, Nagy F, Schäfer E, Fleck C. PLoS One. 2010 May 19;5(5):e10721. 10.1371/journal.pone.0010721
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. Hartleben B, Gödel M, Meyer-Schwesinger C, Liu S, Ulrich T, Köbler S, Wiech T, Grahammer F, Arnold SJ, Lindenmeyer MT, Cohen CD, Pavenstädt H, Kerjaschki D, Mizushima N, Shaw AS, Walz G, Huber TB. J Clin Invest. 2010 Apr;120(4):1084-96. 10.1172/jci39492
BLOS1, a putative BLOC-1 subunit, interacts with SNX1 and modulates root growth in Arabidopsis. Cui Y, Li X, Chen Q, He X, Yang Q, Zhang A, Yu X, Chen H, Liu N, Xie Q, Yang W, Zuo J, Palme K, Li W. J Cell Sci. 2010 Nov 1;123(Pt 21):3727-33. 10.1242/jcs.069732
Control of Dpp morphogen distribution by a secreted feedback regulator. Vuilleumier R., Springhorn A., Patterson L., Koidl S., Hammerschmidt M., Affolter M., Pyrowolakis G. Nat Cell Biol. 2010 Jun;12(6):611-7. 10.1038/ncb2064
DeltaA/DeltaD regulate multiple and temporally distinct phases of notch signaling during dopaminergic neurogenesis in zebrafish. Mahler J, Filippi A, Driever W. J Neurosci. 2010 Dec 8;30(49):16621-35. 10.1523/jneurosci.4769-10.2010
Dicer is required for Sertoli cell function and survival. Kim GJ, Georg I, Scherthan H, Merkenschlager M, Guillou F, Scherer G, Barrionuevo F. Int J Dev Biol. 2010;54(5):867-75. 10.1387/ijdb.092874gk
Differential role of Rab proteins in ciliary trafficking: Rab23 regulates smoothened levels. Boehlke C, Bashkurov M, Buescher A, Krick T, John AK, Nitschke R, Walz G, Kuehn EW. J Cell Sci. 2010 May 1;123(Pt 9):1460-7. 10.1242/jcs.058883
Early functional magnetic resonance imaging activations predict language outcome after stroke. Saur D, Ronneberger O, Kümmerer D, Mader I, Weiller C, Klöppel S. Brain. 2010 Apr;133(Pt 4):1252-64. 10.1093/brain/awq021
Ectodomain shedding generates Neoepitopes on collagen XVII, the major autoantigen for bullous pemphigoid. Nishie W, Lamer S, Schlosser A, Licarete E, Franzke CW, Hofmann SC, Jackow J, Sitaru C, Bruckner-Tuderman L. J Immunol. 2010 Oct 15;185(8):4938-47. 10.4049/jimmunol.1001524
Expression of leucine-rich-repeat-kinase 2 (LRRK2) during embryonic development. Zechel S, Meinhardt A, Unsicker K, von Bohlen Und Halbach O. Int J Dev Neurosci. 2010 Aug;28(5):391-9. 10.1016/j.ijdevneu.2010.04.002
Expression of the paralogous tyrosine hydroxylase encoding genes th1 and th2 reveals the full complement of dopaminergic and noradrenergic neurons in zebrafish larval and juvenile brain. Filippi A, Mahler J, Schweitzer J, Driever W. J Comp Neurol. 2010 Feb 15;518(4):423-38. 10.1002/cne.22213
Functional analysis of amino-terminal domains of the photoreceptor phytochrome B. Palágyi A, Terecskei K, Adám E, Kevei E, Kircher S, Mérai Z, Schäfer E, Nagy F, Kozma-Bognár L. Plant Physiol. 2010 Aug;153(4):1834-45. 10.1104/pp.110.153031
Genetic dissection of dopaminergic and noradrenergic contributions to catecholaminergic tracts in early larval zebrafish. Kastenhuber E, Kratochwil CF, Ryu S, Schweitzer J, Driever W. J Comp Neurol. 2010 Feb 15;518(4):439-58. 10.1002/cne.22214
Go or stop? Divergent roles of Reelin in radial neuronal migration. Zhao S, Frotscher M. Neuroscientist. 2010 Aug;16(4):421-34. 10.1177/1073858410367521
Harmonic filters for 3D multichannel data: rotation invariant detection of mitoses in colorectal cancer. Schlachter M, Reisert M, Herz C, Schlürmann F, Lassmann S, Werner M, Burkhardt H, Ronneberger O. IEEE Trans Med Imaging. 2010 Aug;29(8):1485-95. 10.1109/tmi.2010.2049856
Humic substances induce lateral root formation and expression of the early auxin-responsive IAA19 gene and DR5 synthetic element in Arabidopsis. Trevisan S, Pizzeghello D, Ruperti B, Francioso O, Sassi A, Palme K, Quaggiotti S, Nardi S. Plant Biol (Stuttg). 2010 Jul 1;12(4):604-14. 10.1111/j.1438-8677.2009.00248.x
Inhibition of mitochondrial fusion by a-synuclein is rescued by PINK1, Parkin and DJ-1. Kamp F, Exner N, Lutz AK, Wender N, Hegermann J, Brunner B, Nuscher B, Bartels T, Giese A, Beyer K, Eimer S, Winklhofer KF, Haass C. EMBO J. 2010 Oct 20;29(20):3571-89. 10.1038/emboj.2010.223
Intracellular FRET analysis of lipid/DNA complexes using flow cytometry and fluorescence imaging techniques Schneider S, Lenz D, Holzer M, Palme K, Süss R. J Control Release. 2010 Aug 3;145(3):289-96. 10.1016/j.jconrel.2010.04.016
Inversin relays Frizzled-8 signals to promote proximal pronephros development. Lienkamp S, Ganner A, Boehlke C, Schmidt T, Arnold SJ, Schäfer T, Romaker D, Schuler J, Hoff S, Powelske C, Eifler A, Krönig C, Bullerkotte A, Nitschke R, Kuehn EW, Kim E, Burkhardt H, Brox T, Ronneberger O, Gloy J, Walz G. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20388-93. 10.1073/pnas.1013070107
L1 syndrome mutations impair neuronal L1 function at different levels by divergent mechanisms. Schäfer MK, Nam YC, Moumen A, Keglowich L, Bouché E, Küffner M, Bock HH, Rathjen FG, Raoul C, Frotscher M. Neurobiol Dis. 2010 Oct;40(1):222-37. 10.1016/j.nbd.2010.05.029
L1CAM ubiquitination facilitates its lysosomal degradation. Schäfer MK, Schmitz B, Diestel S. FEBS Lett. 2010 Nov 5;584(21):4475-80. 10.1016/j.febslet.2010.10.011
Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes. Oberle C, Huai J, Reinheckel T, Tacke M, Rassner M, Ekert PG, Buellesbach J, Borner C. Cell Death Differ. 2010 Jul;17(7):1167-78. 10.1038/cdd.2009.214
MGOUN1 encodes an Arabidopsis type IB DNA topoisomerase required in stem cell regulation and to maintain developmentally regulated gene silencing. Graf P, Dolzblasz A, Würschum T, Lenhard M, Pfreundt U, Laux T. Plant Cell. 2010 Mar;22(3):716-28. 10.1105/tpc.109.068296
Modelling polar auxin transport in developmental patterning. Santos F, Teale W, Fleck C, Volpers M, Ruperti B, Palme K. Plant Biol (Stuttg). 2010 Sep;12 Suppl 1:3-14. 10.1111/j.1438-8677.2010.00388.x
Naked dense bodies provoke depression. Hallermann S, Kittel RJ, Wichmann C, Weyhersmüller A, Fouquet W, Mertel S, Owald D, Eimer S, Depner H, Schwärzel M, Sigrist SJ, Heckmann M. J Neurosci. 2010 Oct 27;30(43):14340-5. 10.1523/jneurosci.2495-10.2010
NPHP proteins: gatekeepers of the ciliary compartment. Omran H J Cell Biol. 2010 Sep 6;190(5):715-7. 10.1083/jcb.201008080
Origin, maturation, and astroglial transformation of secondary radial glial cells in the developing dentate gyrus. Brunne B, Zhao S, Derouiche A, Herz J, May P, Frotscher M, Bock HH. Glia. 2010 Oct;58(13):1553-69. 10.1002/glia.21029
Preferential adhesion maintains separation of ommatidia in the Drosophila eye. Bao S, Fischbach KF, Corbin V, Cagan RL. Dev Biol. 2010 Aug 15;344(2):948-56. 10.1016/j.ydbio.2010.06.013
Primary cilia regulate mTORC1 activity and cell size through Lkb1. Boehlke C, Kotsis F, Patel V, Braeg S, Voelker H, Bredt S, Beyer T, Janusch H, Hamann C, Gödel M, Müller K, Herbst M, Hornung M, Doerken M, Köttgen M, Nitschke R, Igarashi P, Walz G, Kuehn EW. Nat Cell Biol. 2010 Nov;12(11):1115-22 10.1038/ncb2117
PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation. Gao H, Wang Y, Wegierski T, Skouloudaki K, Pütz M, Fu X, Engel C, Boehlke C, Peng H, Kuehn EW, Kim E, Kramer-Zucker A, Walz G. Hum Mol Genet. 2010 Jan 1;19(1):16-24. 10.1093/hmg/ddp463
Proper layering is important for precisely timed activation of hippocampal mossy cells. Kowalski J, Geuting M, Paul S, Dieni S, Laurens J, Zhao S, Drakew A, Haas CA, Frotscher M, Vida I. Cereb Cortex. 2010 Sep;20(9):2043-54. 10.1093/cercor/bhp267
Recognition of pre- and postsynaptic neurons via nephrin/NEPH1 homologs is a basis for the formation of the Drosophila retinotopic map. Sugie A, Umetsu D, Yasugi T, Fischbach KF, Tabata T. Development. 2010 Oct;137(19):3303-13. 10.1242/dev.047332
Regulation of Frizzled-dependent planar polarity signaling by a V-ATPase subunit. Hermle T, Saltukoglu D, Grünewald J, Walz G, Simons M. Curr Biol. 2010 Jul 27;20(14):1269-76. 10.1016/j.cub.2010.05.057
Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L). Lindenboim L, Blacher E, Borner C, Stein R. Cell Death Differ. 2010 Feb;17(2):346-59. 10.1038/cdd.2009.145
Regulation of Tbx22 during facial and palatal development. Fuchs A, Inthal A, Herrmann D, Cheng S, Nakatomi M, Peters H, Neubüser A. Dev Dyn. 2010 Nov;239(11):2860-74. 10.1002/dvdy.22421
Role for Reelin in stabilizing cortical architecture. Frotscher M. Trends Neurosci. 2010 Sep;33(9):407-14. 10.1016/j.tins.2010.06.001
Role for Reelin-induced cofilin phosphorylation in the assembly of sympathetic preganglionic neurons in the murine intermediolateral column. Krüger MT, Zhao S, Chai X, Brunne B, Bouché E, Bock HH, Frotscher M. Eur J Neurosci. 2010 Nov;32(10):1611-7. 10.1111/j.1460-9568.2010.07433.x
Seasonal and cell type specific expression of sulfate transporters in the phloem of Populus reveals tree specific characteristics for SO(4)(2-) storage and mobilization. Dürr J, Bücking H, Mult S, Wildhagen H, Palme K, Rennenberg H, Ditengou F, Herschbach C. Plant Mol Biol. 2010 Mar;72(4-5):499-517. 10.1007/s11103-009-9587-6
SnAvi--a new tandem tag for high-affinity protein-complex purification. Schäffer U, Schlosser A, Müller KM, Schäfer A, Katava N, Baumeister R, Schulze E. Nucleic Acids Res. 2010 Apr;38(6):e91. 10.1093/nar/gkp1178
Targeted knock-out of a gene encoding sulfite reductase in the moss Physcomitrella patens affects gametophytic and sporophytic development. Wiedemann G, Hermsen C, Melzer M, Büttner-Mainik A, Rennenberg H, Reski R, Kopriva S. FEBS Lett. 2010 Jun 3;584(11):2271-8. 10.1016/j.febslet.2010.03.034
The polycotyledon (pct1-2) mutant of tomato shows enhanced accumulation of PIN1 auxin transport facilitator protein. Kharshiing EV, Kumar GP, Ditengou FA, Li X, Palme K, Sharma R. Plant Biol (Stuttg). 2010 Jan;12(1):224-8. 10.1111/j.1438-8677.2009.00267.x
The Rac1 regulator ELMO1 controls vascular morphogenesis in zebrafish. Epting D, Wendik B, Bennewitz K, Dietz CT, Driever W, Kroll J. Circ Res. 2010 Jul 9;107(1):45-55. 10.1161/circresaha.109.213983
Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development. Onichtchouk D, Geier F, Polok B, Messerschmidt DM, Mössner R, Wendik B, Song S, Taylor V, Timmer J, Driever W. Mol Syst Biol. 2010;6:354. 10.1038/msb.2010.9

2009

Title

Author

Journal

DOI

A modular diffusion barrier based on phase separation for localized delivery of discrete drug volumes in aqueous environments Steigert J, Strasser M, Wangler N, Brett O, Streule W, Koltay P, Daub M, Zengerle R. Lab Chip. 2009 Jun 21;9(12):1801-5 10.1039/b901279f
A short carboxy-terminal domain of polycystin-1 reorganizes the microtubular network and the endoplasmic reticulum. Gao H, Sellin LK, Pütz M, Nickel C, Imgrund M, Gerke P, Nitschke R, Walz G, Kramer-Zucker AG. Exp Cell Res. 2009 Apr 15;315(7):1157-70. 10.1016/j.yexcr.2009.01.027
A uniquely high number of ftsZ genes in the moss Physcomitrella patens. Martin A, Lang D, Heckmann J, Zimmer AD, Vervliet-Scheebaum M, Reski R. Plant Biol (Stuttg). 2009 Sep;11(5):744-50. 10.1111/j.1438-8677.2008.00174.x
Arabidopsis ASA1 is important for jasmonate-mediated regulation of auxin biosynthesis and transport during lateral root formation. Sun J, Xu Y, Ye S, Jiang H, Chen Q, Liu F, Zhou W, Chen R, Li X, Tietz O, Wu X, Cohen JD, Palme K, Li C. Plant Cell. 2009 May;21(5):1495-511. 10.1105/tpc.108.064303
Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth. Sämann J, Hegermann J, von Gromoff E, Eimer S, Baumeister R, Schmidt E. J Biol Chem. 2009 Jun 12;284(24):16482-91. 10.1074/jbc.m808255200
Challenges to our current view on chloroplasts. Reski R Biol Chem. 2009 Aug;390(8):731-8. 10.1515/bc.2009.089
Conditional inactivation of glucocorticoid receptor gene in dopamine-beta-hydroxylase cells impairs chromaffin cell survival. Parlato R, Otto C, Tuckermann J, Stotz S, Kaden S, Gröne HJ, Unsicker K, Schütz G. Endocrinology. 2009 Apr;150(4):1775-81. 10.1210/en.2008-1107
Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects. Loges NT, Olbrich H, Becker-Heck A, Häffner K, Heer A, Reinhard C, Schmidts M, Kispert A, Zariwala MA, Leigh MW, Knowles MR, Zentgraf H, Seithe H, Nürnberg G, Nürnberg P, Reinhardt R, Omran H. Am J Hum Genet. 2009 Dec;85(6):883-9. 10.1016/j.ajhg.2009.10.018
Development of the dopamine systems in zebrafish. Schweitzer J, Driever W. Adv Exp Med Biol. 2009;651:1-14. 10.1007/978-1-4419-0322-8_1
Differential expression and regulation of olig genes in zebrafish. Tiso N, Filippi A, Benato F, Negrisolo E, Modena N, Vaccari E, Driever W, Argenton F. J Comp Neurol. 2009 Jul 20;515(3):378-96. 10.1002/cne.22054
Dominant-negative effects of COL7A1 mutations can be rescued by controlled overexpression of normal collagen VII. Fritsch A, Spassov S, Elfert S, Schlosser A, Gache Y, Meneguzzi G, Bruckner-Tuderman L. J Biol Chem. 2009 Oct 30;284(44):30248-56. 10.1074/jbc.m109.045294
Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors. Schwenk J, Harmel N, Zolles G, Bildl W, Kulik A, Heimrich B, Chisaka O, Jonas P, Schulte U, Fakler B, Klöcker N. Science. 2009 Mar 6;323(5919):1313-9. 10.1126/science.1167852
Immunofluorescence staining of ciliated respiratory epithelial cells. Omran H, Loges NT. Methods Cell Biol. 2009;91:123-33. 10.1016/s0091-679x(08)91007-4
Impaired dense core vesicle maturation in Caenorhabditis elegans mutants lacking Rab2. Edwards SL, Charlie NK, Richmond JE, Hegermann J, Eimer S, Miller KG. J Cell Biol. 2009 Sep 21;186(6):881-95. 10.1083/jcb.200902095
Increased expression of secreted frizzled-related protein 4 in polycystic kidneys. Romaker D, Puetz M, Teschner S, Donauer J, Geyer M, Gerke P, Rumberger B, Dworniczak B, Pennekamp P, Buchholz B, Neumann HP, Kumar R, Gloy J, Eckardt KU, Walz G. J Am Soc Nephrol. 2009 Jan;20(1):48-56. 10.1681/asn.2008040345
Initiation and maturation of cilia-generated flow in newborn and postnatal mouse airway. Francis RJ, Chatterjee B, Loges NT, Zentgraf H, Omran H, Lo CW. Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L1067-75. 10.1152/ajplung.00001.2009
Kindlin-1 Is required for RhoGTPase-mediated lamellipodia formation in keratinocytes. Has C, Herz C, Zimina E, Qu HY, He Y, Zhang ZG, Wen TT, Gache Y, Aumailley M, Bruckner-Tuderman L. Am J Pathol. 2009 Oct;175(4):1442-52. 10.2353/ajpath.2009.090203
Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome. Huber TB, Hartleben B, Winkelmann K, Schneider L, Becker JU, Leitges M, Walz G, Haller H, Schiffer M. J Am Soc Nephrol. 2009 Apr;20(4):798-806. 10.1681/asn.2008080871
Maturation of active zone assembly by Drosophila Bruchpilot. Fouquet W, Owald D, Wichmann C, Mertel S, Depner H, Dyba M, Hallermann S, Kittel RJ, Eimer S, Sigrist SJ. J Cell Biol. 2009 Jul 13;186(1):129-45. 10.1083/jcb.200812150
Mechanisms of fibroblast cell therapy for dystrophic epidermolysis bullosa: high stability of collagen VII favors long-term skin integrity. Kern JS, Loeckermann S, Fritsch A, Hausser I, Roth W, Magin TM, Mack C, Müller ML, Paul O, Ruther P, Bruckner-Tuderman L. Mol Ther. 2009 Sep;17(9):1605-15. 10.1038/mt.2009.144
Moss (Physcomitrella patens) GH3 proteins act in auxin homeostasis. Ludwig-Müller J, Jülke S, Bierfreund NM, Decker EL, Reski R. New Phytol. 2009 Jan;181(2):323-38. 10.1111/j.1469-8137.2008.02677.x
Netrin-DCC, Robo-Slit, and heparan sulfate proteoglycans coordinate lateral positioning of longitudinal dopaminergic diencephalospinal axons. Kastenhuber E, Kern U, Bonkowsky JL, Chien CB, Driever W, Schweitzer J. J Neurosci. 2009 Jul 15;29(28):8914-26. 10.1523/jneurosci.0568-09.2009
NO VEIN mediates auxin-dependent specification and patterning in the Arabidopsis embryo, shoot, and root. Tsugeki R, Ditengou FA, Sumi Y, Teale W, Palme K, Okada K. Plant Cell. 2009 Oct;21(10):3133-51. 10.1105/tpc.109.068841
Podocyte polarity signalling. Simons M, Hartleben B, Huber TB. Curr Opin Nephrol Hypertens. 2009 Jul;18(4):324-30. 10.1097/mnh.0b013e32832e316d
Predictable and defined microgradients in liquid environment for chemical single cell stimulation N. Wangler, M. Welsche, M. Laufer, A. Träger, N. Paust, M. Thielen, O. Sobolev, G. Roth, R. Zengerle, J. Steigert Proc. of the Thirteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Jeju, Korea, November 1-5, 2009, pp. 679 - 681 No DOI - internal link
Prediction of dual protein targeting to plant organelles. Mitschke J, Fuss J, Blum T, Höglund A, Reski R, Kohlbacher O, Rensing SA. New Phytol. 2009;183(1):224-35. 10.1111/j.1469-8137.2009.02832.x
Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models. Karpinar DP, Balija MB, Kügler S, Opazo F, Rezaei-Ghaleh N, Wender N, Kim HY, Taschenberger G, Falkenburger BH, Heise H, Kumar A, Riedel D, Fichtner L, Voigt A, Braus GH, Giller K, Becker S, Herzig A, Baldus M, Jäckle H, Eimer S, Schulz JB, Griesinger C, Zweckstetter M. EMBO J. 2009 Oct 21;28(20):3256-68. 10.1038/emboj.2009.257
Progressive postnatal motoneuron loss in mice lacking GDF-15. Strelau J, Strzelczyk A, Rusu P, Bendner G, Wiese S, Diella F, Altick AL, von Bartheld CS, Klein R, Sendtner M, Unsicker K. J Neurosci. 2009 Oct 28;29(43):13640-8. 10.1523/jneurosci.1133-09.2009
Rapid single cell transfection by localised and discreate release of DNA-lipid nanoemulsions M. Welsche, N. Wangler, M. Laufer, A. Träger, M. Thielen, M. Daub, R. Zengerle, J. Steigert Proc. of the Thirteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Jeju, Korea, November 1-5, 2009, pp. 1802 – 1804 No DOI - internal link
Redundant and specific roles of the ARGONAUTE proteins AGO1 and ZLL in development and small RNA-directed gene silencing. Mallory AC, Hinze A, Tucker MR, Bouché N, Gasciolli V, Elmayan T, Lauressergues D, Jauvion V, Vaucheret H, Laux T. PLoS Genet. 2009 Sep;5(9):e1000646. 10.1371/journal.pgen.1000646
Reelin and Notch1 cooperate in the development of the dentate gyrus. Sibbe M, Förster E, Basak O, Taylor V, Frotscher M. J Neurosci. 2009 Jul 1;29(26):8578-85. 10.1523/jneurosci.0958-09.2009
Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3. Chai X, Förster E, Zhao S, Bock HH, Frotscher M. J Neurosci. 2009 Jan 7;29(1):288-99. 10.1523/jneurosci.2934-08.2009
Regulation of ciliary polarity by the APC/C. Ganner A, Lienkamp S, Schäfer T, Romaker D, Wegierski T, Park TJ, Spreitzer S, Simons M, Gloy J, Kim E, Wallingford JB, Walz G. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17799-804. 10.1073/pnas.0909465106
Remodeling of aortic smooth muscle during avian embryonic development. Wiegreffe C, Christ B, Huang R, Scaal M. Dev Dyn. 2009 Mar;238(3):624-31. 10.1002/dvdy.21888
Role of Reelin in the development and maintenance of cortical lamination. Frotscher M, Chai X, Bock HH, Haas CA, Förster E, Zhao S. J Neural Transm. 2009 Nov;116(11):1451-5. 10.1007/s00702-009-0228-7
Rotational invariance based on Fourier analysis in polar and spherical coordinates. Wang Q, Ronneberger O, Burkhardt H. IEEE Trans Pattern Anal Mach Intell. 2009 Sep;31(9):1715-22. 10.1109/tpami.2009.29
Salt-dependent regulation of a CNG channel subfamily in Arabidopsis. Kugler A, Köhler B, Palme K, Wolff P, Dietrich P. BMC Plant Biol. 2009 Nov 27;9:140. 10.1186/1471-2229-9-140
Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. Skouloudaki K, Puetz M, Simons M, Courbard JR, Boehlke C, Hartleben B, Engel C, Moeller MJ, Englert C, Bollig F, Schäfer T, Ramachandran H, Mlodzik M, Huber TB, Kuehn EW, Kim E, Kramer-Zucker A, Walz G. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8579-84. 10.1073/pnas.0811691106
Signaling at the slit: podocytes chat by synaptic transmission. Weide T, Huber TB. J Am Soc Nephrol. 2009 Sep;20(9):1862-4. 10.1681/asn.2009070691
Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Barrionuevo F, Georg I, Scherthan H, Lécureuil C, Guillou F, Wegner M, Scherer G. Dev Biol. 2009 Mar 15;327(2):301-12. 10.1016/j.ydbio.2008.12.011
The AUXIN BINDING PROTEIN 1 is required for differential auxin responses mediating root growth. Tromas A, Braun N, Muller P, Khodus T, Paponov IA, Palme K, Ljung K, Lee JY, Benfey P, Murray JA, Scheres B, Perrot-Rechenmann C. PLoS One. 2009 Sep 24;4(9):e6648. 10.1371/journal.pone.0006648
The ectomycorrhizal fungus Laccaria bicolor stimulates lateral root formation in poplar and Arabidopsis through auxin transport and signaling. Felten J, Kohler A, Morin E, Bhalerao RP, Palme K, Martin F, Ditengou FA, Legué V. Plant Physiol. 2009 Dec;151(4):1991-2005. 10.1104/pp.109.147231
The histidine kinases CYTOKININ-INDEPENDENT1 and ARABIDOPSIS HISTIDINE KINASE2 and 3 regulate vascular tissue development in Arabidopsis shoots. Hejátko J, Ryu H, Kim GT, Dobesová R, Choi S, Choi SM, Soucek P, Horák J, Pekárová B, Palme K, Brzobohaty B, Hwang I. Plant Cell. 2009 Jul;21(7):2008-21. 10.1105/tpc.109.066696
The irre cell recognition module (IRM) proteins. Fischbach KF, Linneweber GA, Andlauer TF, Hertenstein A, Bonengel B, Chaudhary K. J Neurogenet. 2009;23(1-2):48-67. 10.1080/01677060802471668
The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation. Shen ZJ, Esnault S, Schinzel A, Borner C, Malter JS. Nat Immunol. 2009 Mar;10(3):257-65. 10.1038/ni.1697
The planar cell polarity (PCP) protein Diversin translocates to the nucleus to interact with the transcription factor AF9. Haribaskar R, Pütz M, Schupp B, Skouloudaki K, Bietenbeck A, Walz G, Schäfer T. Biochem Biophys Res Commun. 2009 Sep 11;387(1):212-7. 10.1016/j.bbrc.2009.07.012
TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum. Wegierski T, Steffl D, Kopp C, Tauber R, Buchholz B, Nitschke R, Kuehn EW, Walz G, Köttgen M. EMBO J. 2009 Mar 4;28(5):490-9. 10.1038/emboj.2008.307
Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli. Wegierski T, Lewandrowski U, Müller B, Sickmann A, Walz G. J Biol Chem. 2009 Jan 30;284(5):2923-33. 10.1074/jbc.m805357200
UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans. Sumakovic M, Hegermann J, Luo L, Husson SJ, Schwarze K, Olendrowitz C, Schoofs L, Richmond J, Eimer S. J Cell Biol. 2009 Sep 21;186(6):897-914. 10.1083/jcb.200902096
XuvTools: free, fast and reliable stitching of large 3D datasets. Emmenlauer M, Ronneberger O, Ponti A, Schwarb P, Griffa A, Filippi A, Nitschke R, Driever W, Burkhardt H. J Microsc. 2009 Jan;233(1):42-60. 10.1111/j.1365-2818.2008.03094.x
Zebrafish collagen XII is present in embryonic connective tissue sheaths (fascia) and basement membranes. Bader HL, Keene DR, Charvet B, Veit G, Driever W, Koch M, Ruggiero F. Matrix Biol. 2009 Jan;28(1):32-43. 10.1016/j.matbio.2008.09.580
Zebrafish diencephalic A11-related dopaminergic neurons share a conserved transcriptional network with neuroendocrine cell lineages. Löhr H, Ryu S, Driever W. Development. 2009 Mar;136(6):1007-17. 10.1242/dev.033878

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A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy. Fritsch A, Loeckermann S, Kern JS, Braun A, Bösl MR, Bley TA, Schumann H, von Elverfeldt D, Paul D, Erlacher M, Berens von Rautenfeld D, Hausser I, Fässler R, Bruckner-Tuderman L. J Clin Invest. 2008 May;118(5):1669-79. 10.1172/JCI34292.
A new gene for auxin synthesis. Palme K, Nagy F. Cell. 2008 Apr 4;133(1):31-2. 10.1016/j.cell.2008.03.014
A PIIB-type Ca2+-ATPase is essential for stress adaptation in Physcomitrella patens. Qudeimat E, Faltusz AM, Wheeler G, Lang D, Holtorf H, Brownlee C, Reski R, Frank W. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19555-60. 10.1016/j.cell.2008.03.014
Alginate bead fabrication and encapsulation of living cells under centrifugally induced artificial gravity conditions. Haeberle S, Naegele L, Burger R, von Stetten F, Zengerle R, Ducrée J. J Microencapsul. 2008 Jun;25(4):267-74. 10.1080/02652040801954333
Alterations of the cytoskeleton in all three embryonic lineages contribute to the epiboly defect of Pou5f1/Oct4 deficient MZspg zebrafish embryos. Lachnit M, Kur E, Driever W. Dev Biol. 2008 Mar 1;315(1):1-17. 10.1016/j.ydbio.2007.10.008
Apoptosis induced by Semliki Forest virus is RNA replication dependent and mediated via Bak. Urban C, Rhême C, Maerz S, Berg B, Pick R, Nitschke R, Borner C. Cell Death Differ. 2008 Sep;15(9):1396-407. 10.1038/cdd.2008.61
Auxin as a model for the integration of hormonal signal processing and transduction. Teale WD, Ditengou FA, Dovzhenko AD, Li X, Molendijk AM, Ruperti B, Paponov I, Palme K. Mol Plant. 2008 Mar;1(2):229-37. 10.1093/mp/ssn006
Comprehensive transcriptome analysis of auxin responses in Arabidopsis. Paponov IA, Paponov M, Teale W, Menges M, Chakrabortee S, Murray JA, Palme K. Mol Plant. 2008 Mar;1(2):321-37. 10.1093/mp/ssm021
Coordinated regulation of Arabidopsis thaliana development by light and gibberellins. Feng S, Martinez C, Gusmaroli G, Wang Y, Zhou J, Wang F, Chen L, Yu L, Iglesias-Pedraz JM, Kircher S, Schäfer E, Fu X, Fan LM, Deng XW. Nature. 2008 Jan 24;451(7177):475-9. 10.1038/nature06448
DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm. Loges NT, Olbrich H, Fenske L, Mussaffi H, Horvath J, Fliegauf M, Kuhl H, Baktai G, Peterffy E, Chodhari R, Chung EM, Rutman A, O'Callaghan C, Blau H, Tiszlavicz L, Voelkel K, Witt M, Zietkiewicz E, Neesen J, Reinhardt R, Mitchison HM, Omran H. Am J Hum Genet. 2008 Nov;83(5):547-58. 10.1016/j.ajhg.2008.10.001
Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish. Reichenbach B, Delalande JM, Kolmogorova E, Prier A, Nguyen T, Smith CM, Holzschuh J, Shepherd IT Dev Biol. 2008 Jun 1;318(1):52-64. 10.1016/j.ydbio.2008.02.061
Flow modulates centriole movements in tubular epithelial cells. Kotsis F, Nitschke R, Doerken M, Walz G, Kuehn EW. Pflugers Arch. 2008 Sep;456(6):1025-35. 10.1007/s00424-008-0475-8
Genetic and physical interaction between the NPHP5 and NPHP6 gene products. Schäfer T, Pütz M, Lienkamp S, Ganner A, Bergbreiter A, Ramachandran H, Gieloff V, Gerner M, Mattonet C, Czarnecki PG, Sayer JA, Otto EA, Hildebrandt F, Kramer-Zucker A, Walz G. Hum Mol Genet. 2008 Dec 1;17(23):3655-62. 10.1093/hmg/ddn260
It's not all about nephrin. Simons M, Huber TB. Kidney Int. 2008 Mar;73(6):671-3. 10.1038/sj.ki.5002798
JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis. Schmitt-Graeff AH, Teo SS, Olschewski M, Schaub F, Haxelmans S, Kirn A, Reinecke P, Germing U, Skoda RC. Haematologica. 2008 Jan;93(1):34-40. 10.3324/haematol.11581
KIBRA modulates directional migration of podocytes. Duning K, Schurek EM, Schlüter M, Bayer M, Reinhardt HC, Schwab A, Schaefer L, Benzing T, Schermer B, Saleem MA, Huber TB, Bachmann S, Kremerskothen J, Weide T, Pavenstädt H. J Am Soc Nephrol. 2008 Oct;19(10):1891-903. 10.1681/asn.2007080916
Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia. Bergmann C, Fliegauf M, Brüchle NO, Frank V, Olbrich H, Kirschner J, Schermer B, Schmedding I, Kispert A, Kränzlin B, Nürnberg G, Becker C, Grimm T, Girschick G, Lynch SA, Kelehan P, Senderek J, Neuhaus TJ, Stallmach T, Zentgraf H, Nürnberg P, Gretz N, Lo C, Lienkamp S, Schäfer T, Walz G, Benzing T, Zerres K, Omran H. Am J Hum Genet. 2008 Apr;82(4):959-70. 10.1016/j.ajhg.2008.02.017
Mechanical induction of lateral root initiation in Arabidopsis thaliana. Ditengou FA, Teale WD, Kochersperger P, Flittner KA, Kneuper I, van der Graaff E, Nziengui H, Pinosa F, Li X, Nitschke R, Laux T, Palme K. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18818-23. 10.1073/pnas.0807814105
Molecular pathogenesis of proteinuria. Huber TB. Dtsch Med Wochenschr. 2008 May;133(18):954-8. 10.1055/s-2008-1075673
Mutation of the rice Narrow leaf1 gene, which encodes a novel protein, affects vein patterning and polar auxin transport. Qi J, Qian Q, Bu Q, Li S, Chen Q, Sun J, Liang W, Zhou Y, Chu C, Li X, Ren F, Palme K, Zhao B, Chen J, Chen M, Li C. Plant Physiol. 2008 Aug;147(4):1947-59. 10.1104/pp.108.118778
Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. Hartleben B, Schweizer H, Lübben P, Bartram MP, Möller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB. J Biol Chem. 2008 Aug 22;283(34):23033-8. 10.1074/jbc.m803143200
Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin. Lüke Y, Zaim H, Karakesisoglou I, Jaeger VM, Sellin L, Lu W, Schneider M, Neumann S, Beijer A, Munck M, Padmakumar VC, Gloy J, Walz G, Noegel AA. J Cell Sci. 2008 Jun 1;121(Pt 11):1887-98. 10.1242/jcs.019075
Organogenic nodule development in hop (Humulus lupulus L.): transcript and metabolic responses. Fortes AM, Santos F, Choi YH, Silva MS, Figueiredo A, Sousa L, Pessoa F, Santos BA, Sebastiana M, Palme K, Malhó R, Verpoorte R, Pais MS. BMC Genomics. 2008 Sep 29;9:445. doi: 10.1186/1471-2164-9-445. 10.1186/1471-2164-9-445
Pericytes in the mature chorioallantoic membrane capillary plexus contain desmin and alpha-smooth muscle actin: relevance for non-sprouting angiogenesis. Kurz H, Fehr J, Nitschke R, Burkhardt H. Histochem Cell Biol. 2008 Nov;130(5):1027-40. 10.1007/s00418-008-0478-8
Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development. Huber K, Franke A, Brühl B, Krispin S, Ernsberger U, Schober A, von Bohlen und Halbach O, Rohrer H, Kalcheim C, Unsicker K. Neural Dev. 2008 Oct 22;3:28. 10.1186/1749-8104-3-28
Podocytes use FcRn to clear IgG from the glomerular basement membrane. Akilesh S, Huber TB, Wu H, Wang G, Hartleben B, Kopp JB, Miner JH, Roopenian DC, Unanue ER, Shaw AS. Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):967-72. 10.1073/pnas.0711515105
Polyunsaturated fatty acids influence synaptojanin localization to regulate synaptic vesicle recycling. Marza E, Long T, Saiardi A, Sumakovic M, Eimer S, Hall DH, Lesa GM. Mol Biol Cell. 2008 Mar;19(3):833-42. 10.1091/mbc.e07-07-0719
Primary ciliary dyskinesia associated with normal axoneme ultrastructure is caused by DNAH11 mutations. Schwabe GC, Hoffmann K, Loges NT, Birker D, Rossier C, de Santi MM, Olbrich H, Fliegauf M, Failly M, Liebers U, Collura M, Gaedicke G, Mundlos S, Wahn U, Blouin JL, Niggemann B, Omran H, Antonarakis SE, Bartoloni L. Hum Mutat. 2008 Feb;29(2):289-98. 10.1002/humu.20656
Psoriasis regulates epidermal development in zebrafish. Webb AE, Driever W, Kimelman D. Dev Dyn. 2008 Apr;237(4):1153-64. 10.1002/dvdy.21509
Quantum dots versus organic dyes as fluorescent labels. Resch-Genger U, Grabolle M, Cavaliere-Jaricot S, Nitschke R, Nann T. Nat Methods. 2008 Sep;5(9):763-75. 10.1038/nmeth.1248
RBP4 disrupts vitamin A uptake homeostasis in a STRA6-deficient animal model for Matthew-Wood syndrome. Isken A, Golczak M, Oberhauser V, Hunzelmann S, Driever W, Imanishi Y, Palczewski K, von Lintig J. Cell Metab. 2008 Mar;7(3):258-68. 10.1016/j.cmet.2008.01.009
SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans. Neumann-Haefelin E, Qi W, Finkbeiner E, Walz G, Baumeister R, Hertweck M. Genes Dev. 2008 Oct 1;22(19):2721-35. 10.1101/gad.478408
Side population does not define stem cell-like cancer cells in the adrenocortical carcinoma cell line NCI h295R. Lichtenauer UD, Shapiro I, Geiger K, Quinkler M, Fassnacht M, Nitschke R, Rückauer KD, Beuschlein F. Endocrinology. 2008 Mar;149(3):1314-22. 10.1210/en.2007-1001
Sox9 is required for invagination of the otic placode in mice. Barrionuevo F, Naumann A, Bagheri-Fam S, Speth V, Taketo MM, Scherer G, Neubüser A. Dev Biol. 2008 May 1;317(1):213-24. 10.1016/j.ydbio.2008.02.011
Specific gene silencing by artificial MicroRNAs in Physcomitrella patens: an alternative to targeted gene knockouts. Khraiwesh B, Ossowski S, Weigel D, Reski R, Frank W. Plant Physiol. 2008 Oct;148(2):684-93. 10.1104/pp.108.128025
Sterol-dependent endocytosis mediates post-cytokinetic acquisition of PIN2 auxin efflux carrier polarity. Men S, Boutté Y, Ikeda Y, Li X, Palme K, Stierhof YD, Hartmann MA, Moritz T, Grebe M. Nat Cell Biol. 2008 Feb;10(2):237-44. 10.1038/ncb1686
Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes. Walter D, Schmich K, Vogel S, Pick R, Kaufmann T, Hochmuth FC, Haber A, Neubert K, McNelly S, von Weizsäcker F, Merfort I, Maurer U, Strasser A, Borner C. Hepatology. 2008 Dec;48(6):1942-53. 10.1002/hep.22541
Targeting retinal dopaminergic neurons in tyrosine hydroxylase-driven green fluorescent protein transgenic zebrafish. Meng S, Ryu S, Zhao B, Zhang DQ, Driever W, McMahon DG. Mol Vis. 2008;14:2475-83. DOI missing only PMC2610293
The subcellular localization of TRPP2 modulates its function. Fu X, Wang Y, Schetle N, Gao H, Pütz M, von Gersdorff G, Walz G, Kramer-Zucker AG. J Am Soc Nephrol. 2008 Jul;19(7):1342-51. 10.1681/asn.2007070730
TrkB but not trkC receptors are necessary for postnatal maintenance of hippocampal spines. von Bohlen und Halbach O, Minichiello L, Unsicker K. Neurobiol Aging. 2008 Aug;29(8):1247-55. 10.1016/j.neurobiolaging.2007.02.028
TRPP2 and TRPV4 form a polymodal sensory channel complex. Köttgen Michael, Buchholz Björn, Garcia-Gonzalez Miguel A., Kotsis Fruzsina, Fu Xiao, Doerken Mara, Boehlke Christopher, Steffl Daniel, Tauber Robert, Wegierski Tomasz, Nitschke Roland, Suzuki Makoto, Kramer-Zucker Albrecht, Germino Greg G., Watnick Terry, Prenen Jean, Nilius Bernd, Kuehn E. Wolfgang*, and Walz Gerd*. * corresponding authors J Cell Biol. 2008 Aug 11;182(3):437-47. 10.1083/jcb.200805124

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Bsx Is Essential for Differentiation of Multiple Neuromodulatory Cell Populations in the Secondary Prosencephalon Schredelseker T, Veit F, Dorsky RI, Driever W. Front Neurosci. 2020 Jun 3;14:525. 10.3389/fnins.2020.00525 2020
Cortical activity at different time scales: high-pass filtering separates motor planning and execution. Eriksson, D., Heiland, M., Schneider, A. & Diester, I. BioRxiv. DOI: https://doi.org/10.1101/857300 BioRxiv. DOI: https://doi.org/10.1101/857300 2020
Force-responsive Zyxin modulation in periodontal ligament cells is regulated by YAP rather than TAZ. Belgardt E, Steinberg T, Husari A, Dieterle MP, Hülter-Hassler D, Jung B, Tomakidi P. Cell Signal. 2020 Aug;72:109662. 10.1016/j.cellsig.2020.109662 2020
Conserved Genoarchitecture of the Basal Hypothalamus in Zebrafish Embryos Schredelseker T, Driever W. Front Neuroanat. 2020 Feb 6;14:3. 10.3389/fnana.2020.00003 2020
A changing signaling environment induces multiciliated cell trans-differentiation during developmental remodeling Alexia Tasca, Martin Helmstädter, Magdalena Brislinger, Maximilian Haas, Peter Walentek https://www.biorxiv.org 10.1101/2020.04.16.045401 2020
Image-derived models of cell organization changes during differentiation and drug treatments Ruan X, Johnson GR, Bierschenk I, Nitschke R, Boerries M, Busch H, Murphy RF Mol Biol Cell. 2020 Mar 19;31(7):655-666 10.1091/mbc.E19-02-0080 2020
A Joint Action in Times of Pandemic: The German BioImaging Recommendations for Operating Imaging Core Facilities During the SARS-Cov-2 Emergency Dietzel S, Ferrando-May E, Fried H, Kukat C, Naumann A, Nitschke R, Pasierbek P, Peychl J, Rasse TM, Schroth-Diez B, Stöckl MT, Terjung S, Thuenauer R, Tulok S, Weidtkamp-Peters S; German BioImaging-Society for Microscopy and Image Analysis. Cytometry A. 2020 Sep;97(9):882-886 10.1002/cyto.a.24178 2020
The acetyltransferase p300 regulates NRF2 stability and localization Ganner A, Pfeiffer ZC, Wingendorf L, Kreis S, Klein M, Walz G, Neumann-Haefelin E. . Biochem Biophys Res Commun. 2020 Apr 16;524(4):895-902. 10.1016/j.bbrc.2020.02.006 2020
Color vision in insects: insights from Drosophila Schnaitmann C, Pagni M, Reiff DF. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2020 Mar;206(2):183-198 10.1007/s00359-019-01397-3 2020
Optogenetic control of gene expression in plants in the presence of ambient white light Ochoa-Fernandez R, Abel NB, Wieland FG, Schlegel J, Koch LA, Miller JB, Engesser R, Giuriani G, Brandl SM, Timmer J, Weber W, Ott T, Simon R, Zurbriggen MD. Nat Methods. 2020 Jul;17(7):717-725. 10.1038/s41592-020-0868-y 2020
Metabolic profiling in human fibroblasts enables subtype clustering in glycogen storage disease Luciana Hannibal, Jule Theimer, Victoria Wingert, Katharina Klotz, Iris Bierschenk, Roland Nitschke, Ute Spiekerkoetter, Sarah C Grünert Frontiers in Endocrinology, section Cellular Endocrinology in press 2020
The Medicago truncatula DREPP Protein Triggers Microtubule Fragmentation in Membrane Nanodomains during Symbiotic Infections Su C, Klein ML, Hernández-Reyes C, Batzenschlager M, Ditengou FA, Lace B, Keller J, Delaux PM, Ott T. Plant Cell. 2020 May;32(5):1689-1702. 10.1105/tpc.19.00777 2020
Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling Pous L, Deshpande SS, Nath S, Mezey S, Malik SC, Schildge S, Bohrer C, Topp K, Pfeifer D, Fernández-Klett F, Doostkam S, Galanakis DK, Taylor V, Akassoglou K, Schachtrup C. Nat Commun. 2020 Jan 31;11(1):630 10.1038/s41467-020-14466-y 2020
Phytochrome-Based Extracellular Matrix with Reversibly Tunable Mechanical Properties. Hörner M, Raute K, Hummel B, Madl J, Creusen G, Thomas OS, Christen EH, Hotz N, Gübeli RJ, Engesser R, Rebmann B, Lauer J, Rolauffs B, Timmer J, Schamel WWA, Pruszak J, Römer W, Zurbriggen MD, Friedrich C, Walther A, Minguet S, Sawarkar R, Weber W. Adv Mater. 2019 Mar;31(12) 10.1002/adma.201806727 2019
Optogenetic control of integrin-matrix interaction. Baaske J, Mühlhäuser WWD, Yousefi OS, Zanner S, Radziwill G, Hörner M, Schamel WWA, Weber W. Commun Biol. 2019 Jan 8;2:15 10.1038/s42003-018-0264-7 2019
U-Net: deep learning for cell counting, detection, and morphometry. Falk T, Mai D, Bensch R, Çiçek Ö, Abdulkadir A, Marrakchi Y, Böhm A, Deubner J, Jäckel Z, Seiwald K, Dovzhenko A, Tietz O, Bosco CD, Walsh S, Saltukoglu D, Tay TL, Prinz M, Palme K, Simons M, Diester I, Brox T, Ronneberger O. Nat Methods. 2019 Jan;16(1):67-70 10.1038/s41592-019-0356-4 2019
JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress. Cosolo A, Jaiswal J, Csordás G, Grass I, Uhlirova M, Classen AK Elife. 2019 Feb 8;8:e41036. 10.7554/eLife.41036 2019
Auxin-Induced Plasma Membrane Depolarization Is Regulated by Auxin Transport and Not by AUXIN BINDING PROTEIN1. Paponov IA, Dindas J, Król E, Friz T, Budnyk V, Teale W, Paponov M, Hedrich R, Palme K. Front Plant Sci. 2019 Jan 17;9:1953. 10.3389/fpls.2018.01953 2019
Response of Drosophila epithelial cell and tissue shape to external forces in vivo Balaji R, Weichselberger V, Classen AK. Development. 2019 Sep 6;146(17 10.1242/dev.171256 2019
TBC1D8B Mutations Implicate RAB11-Dependent Vesicular Trafficking in the Pathogenesis of Nephrotic Syndrome Kampf LL, Schneider R, Gerstner L, Thünauer R, Chen M, Helmstädter M, Amar A, Onuchic-Whitford AC, Loza Munarriz R, Berdeli A, Müller D, Schrezenmeier E, Budde K, Mane S, Laricchia KM, Rehm HL, MacArthur DG, Lifton RP, Walz G, Römer W, Bergmann C, Hildebrandt F, Hermle T. J Am Soc Nephrol. 2019 Dec;30(12):2338-2353. 10.1681/ASN.2019040414 2019
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria Teumer A, Li Y, Ghasemi S, Prins BP, Wuttke M, Hermle T, Giri A, Sieber KB, Qiu C, Kirsten H, Tin A, Chu AY, Bansal N, Feitosa MF, Wang L, Chai JF, Cocca M, Fuchsberger C, Gorski M, Hoppmann A, Horn K, Li M, Marten J, Noce D, Nutile T, Sedaghat S, Sveinbjornsson G, Tayo BO, van der Most PJ, Xu Y, Yu Z, Gerstner L, Ärnlöv J, Bakker SJL, Baptista D, Biggs ML, Boerwinkle E, Brenner H, Burkhardt R, Carroll RJ, Chee ML, Chee ML, Chen M, Cheng CY, Cook JP, Coresh J, Corre T, Danesh J, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Degenhardt F, Dittrich K, Divers J, Eckardt KU, Ehret G, Endlich K, Felix JF, Franco OH, Franke A, Freedman BI, Freitag-Wolf S, Gansevoort RT, Giedraitis V, Gögele M, Grundner-Culemann F, Gudbjartsson DF, Gudnason V, Hamet P, Harris TB, Hicks AA, Holm H, Foo VHX, Hwang SJ, Ikram MA, Ingelsson E, Jaddoe VWV, Jakobsdottir J, Josyula NS, Jung B, Kähönen M, Khor CC, Kiess W, Koenig W, Körner A, Kovacs P, Kramer H, Krämer BK, Kronenberg F, Lange LA, Langefeld CD, Lee JJ, Lehtimäki T, Lieb W, Lim SC, Lind L, Lindgren CM, Liu J, Loeffler M, Lyytikäinen LP, Mahajan A, Maranville JC, Mascalzoni D, McMullen B, Meisinger C, Meitinger T, Miliku K, Mook-Kanamori DO, Müller-Nurasyid M, Mychaleckyj JC, Nauck M, Nikus K, Ning B, Noordam R, Connell JO, Olafsson I, Palmer ND, Peters A, Podgornaia AI, Ponte B, Poulain T, Pramstaller PP, Rabelink TJ, Raffield LM, Reilly DF, Rettig R, Rheinberger M, Rice KM, Rivadeneira F, Runz H, Ryan KA, Sabanayagam C, Saum KU, Schöttker B, Shaffer CM, Shi Y, Smith AV, Strauch K, Stumvoll M, Sun BB, Szymczak S, Tai ES, Tan NYQ, Taylor KD, Teren A, Tham YC, Thiery J, Thio CHL, Thomsen H, Thorsteinsdottir U, Tönjes A, Tremblay J, Uitterlinden AG, van der Harst P, Verweij N, Vogelezang S, Völker U, Waldenberger M, Wang C, Wilson OD, Wong C, Wong TY, Yang Q, Yasuda M, Akilesh S, Bochud M, Böger CA, Devuyst O, Edwards TL, Ho K, Morris AP, Parsa A, Pendergrass SA, Psaty BM, Rotter JI, Stefansson K, Wilson JG, Susztak K, Snieder H, Heid IM, Scholz M, Butterworth AS, Hung AM, Pattaro C, Köttgen A. Nat Commun. 2019 Sep 11;10(1):4130. 10.1038/s41467-019-11576-0 2019
?N-Tp63 Mediates Wnt/ß-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia. Haas M, Gómez Vázquez JL, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P. Cell Rep. 2019 Sep 24;28(13):3338-3352.e6. 10.1016/j.celrep.2019.08.063 2019
Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling. Kvainickas A, Nägele H, Qi W, Dokládal L, Jimenez-Orgaz A, Stehl L, Gangurde D, Zhao Q, Hu Z, Dengjel J, De Virgilio C, Baumeister R, Steinberg F. J Cell Biol. 2019 Sep 2;218(9):3019-3038. 10.1083/jcb.201812110 2019
Rapid spheroid clearing on a microfluidic chip Silva Santisteban T, Rabajania O, Kalinina I, Robinson S, Meier M. Lab Chip. 2017 Dec 19;18(1):153-161 10.1039/c7lc01114h 2019
CBP-1/p300 acetyltransferase regulates SKN-1/Nrf cellular levels, nuclear localization, and activity in C. elegans Ganner A, Gerber J, Ziegler AK, Li Y, Kandzia J, Matulenski T, Kreis S, Breves G, Klein M, Walz G, Neumann-Haefelin E. Exp Gerontol, 2019 Oct 15;126:110690. 10.1016/j.exger.2019.110690 2019
Divergent function of polycystin 1 and polycystin 2 in cell size regulation Viau A, Kotsis F, Boehlke C, Braeg S, Klein M, Nitschke R, Walz G, Kuehn EW. Biochem Biophys Res Commun. 2020 Jan 8;521(2):290-295 10.1016/j.bbrc.2019.10.074 2019
AWD regulates timed activation of BMP signaling in intestinal stem cells to maintain tissue homeostasis Tracy Cai X, Li H, Safyan A, Gawlik J, Pyrowolakis G, Jasper H. Nat Commun. 2019 Jul 5;10(1):2988. 10.1038/s41467-019-10926-2 2019
A GmNINa-miR172c-NNC1 Regulatory Network Coordinates the Nodulation and Autoregulation of Nodulation Pathways in Soybean Wang L, Sun Z, Su C, Wang Y, Yan Q, Chen J, Ott T, Li X. Mol Plant. 2019 Sep 2;12(9):1211-1226. 10.1016/j.molp.2019.06.002 2019
Sequence environment of BMP-dependent activating elements controls transcriptional responses to Dpp signaling in Drosophila Chayengia M, Veikkolainen V, Jevtic M, Pyrowolakis G. Development 2019 146: dev176107 10.1242/dev.176107 2019
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Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation Jordão MJC, Sankowski R, Brendecke SM, Sagar, Locatelli G, Tai YH, Tay TL, Schramm E, Armbruster S, Hagemeyer N, Groß O, Mai D, Çiçek Ö, Falk T, Kerschensteiner M, Grün D, Prinz M. Science. 2019 Jan 25;363(6425):eaat7554 10.1126/science.aat7554 2019
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A single homeobox gene triggers phase transition, embryogenesis and asexual reproduction. Horst, N.A., A. Katz, I. Pereman, E.L. Decker, N. Ohad, R. Reski Nature Plants 2, 15209. 10.1038/nplants.2015.209 2016
Analysis of confocal image data of Physcomitrella chloroplasts to reveal adaptation principles leading to structural stability at the nano scale. Asgharzadeh, P., B. Özdemir, Stefanie J. Müller, R. Reski, O. Röhrle Proceedings in Applied Mathematics and Mechanics 16, 69-70. 10.1002/pamm.201610023 2016
Calcium buffer proteins are specific markers of human retinal neurons Kántor O, Mezey S, Adeghate J, Naumann A, Nitschke R, Énzsöly A, Szabó A, Lukáts Á, Németh J, Somogyvári Z, Völgyi B. Cell Tissue Res. 2016 Jul;365(1):29-50 10.1007/s00441-016-2376-z 2016
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Characterization of connexin36 gap junctions in the human outer retina. Kántor O, Benko Z, Énzsöly A, Dávid C, Naumann A, Nitschke R, Szabó A, Pálfi E, Orbán J, Nyitrai M, Németh J, Szél Á, Lukáts Á, Völgyi B. Brain Struct Funct. 2016 Jul;221(6):2963-84. 10.1007/s00429-015-1082-z 2016
Characterization of photomorphogenic responses and signaling cascades controlled by phytochrome-A expressed in different tissues. Kirchenbauer D, Viczián A, Ádám É, Hegedus Z, Klose C, Leppert M, Hiltbrunner A, Kircher S, Schäfer E, Nagy F New Phytologist Volume 211, Issue 2 10.1111/nph.13941 2016
Chloroplast FBPase and SPBase are thioredoxin-linked enzymes with similar architecture but different evolutionary histories. Gütle, D.D., T. Roret, S.J. Mueller, J. Couturier, S.D. Lemaire, A. Hecker, T. Dhalleine, B.B. Buchanan, R. Reski, O. Einsle, J.P. Jacquot Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):6779-84 10.1073/pnas.1606241113 2016
Direct Reprogramming of Fibroblasts into Renal Tubular Epithelial Cells by Defined Transcription Factors. Kaminski M, Tosic J, Kresbach C, Engel H, Klockenbusche J, Müller A-L, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS. Nat Cell Biol. 2016 Dec;18(12):1269-1280 10.1038/ncb3437 2016
Identification of targets and interaction partners of arginyl-tRNA protein transferase in the moss Physcomitrella patens. Hoernstein, S.N.W., S.J. Mueller, K. Fiedler, M. Schuelke, J.T. Vanselow, C. Schuessele, D. Lang, R. Nitschke, G.L. Igloi, A. Schlosser, R. Reski Mol Cell Proteomics. 2016 Jun;15(6):1808-22. 10.1074/mcp.M115.057190 2016
Monoallelic Mutations in the Translation Initiation Codon of KLHL24 Cause Skin Fragility. He Y, Maier K, Leppert J, Hausser I, Schwieger-Briel A, Weibel L, Theiler M, Kiritsi D, Busch H, Boerries M, Hannula-Jouppi K, Heikkilä H, Tasanen K, Castiglia D, Zambruno G, Has C. Am J Hum Genet 99:1395-1404, 2016 10.1016/j.ajhg.2016.11.005 2016
Origin and function of stomata in the moss Physcomitrella patens. Chater, C.C., R.S. Caine, M. Tomek, S. Wallace, Y. Kamisugi, A.C. Cuming, D. Lang, C.A. MacAlister, S. Casson, D.C. Bergmann, E.L. Decker, W. Frank, J.E. Gray, A. Fleming, R. Reski, D.J. Beerling Nat Plants. 2016 Nov 28;2:16179 10.1038/nplants.2016.179 2016
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Single Amino Acid Deletion in Kindlin-1 Results in Partial Protein Degradation Which Can Be Rescued by Chaperone Treatment. Maier K, He Y, Esser PR, Thriene K, Sarca D, Kohlhase J, Dengjel J, Martin L, Has C. J Invest Dermatol. 2016 May;136(5):920-929. 10.1016/j.jid.2015.12.039 2016
Spatio-temporal patterning of arginyl-tRNA protein transferase (ATE) contributes to gametophytic development in a moss. Schuessele, C., S.N.W. Hoernstein, S.J. Mueller, M. Rodriguez-Franco, T. Lorenz, D. Lang, G.L. Igloi, R. Reski New Phytol. 2016 Feb;209(3):1014-27 10.1111/nph.13656 2016
The Polycomb group protein CLF emerges as a specific tri-methylase of H3K27 regulating gene expression and development in Physcomitrella patens. Pereman, I., A. Mosquna, A. Katz, G. Wiedemann, D. Lang, E.L. Decker, Y. Tamada, T. Ishikawa, T. Nishiyama, M. Hasebe, R. Reski, N. Ohad Biochim Biophys Acta. 2016 Jul;1859(7):860-70. 10.1016/j.bbagrm.2016.05.004 2016
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UV-B-induced cutaneous inflammation and prospects for antioxidant treatment in Kindler syndrome. Maier K, He Y, Wölfle U, Esser PR, Brummer T, Schempp C, Bruckner-Tuderman L, Has C. Hum Mol Genet 25:5339-5352, 2016 10.1093/hmg/ddw350 2016
A Cilia Independent Role of Ift88/Polaris during Cell Migration. Boehlke C, Janusch H, Hamann C, Powelske C, Mergen M, Herbst H, Kotsis F, Nitschke R, and Kuehn EW. PLoS One 10, e0140378 (2015) doi.org/10.1371/journal.pone.0140378 2015
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Astrocyte uncoupling as a cause of human temporal lobe epilepsy Bedner P, Dupper A, Hüttmann K, Müller J, Herde MK, Dublin P, Deshpande T, Schramm J, Häussler U, Haas CA, Henneberger C, Theis M, Steinhäuser C. Brain. 2015 May;138(Pt 5):1208-22 10.1093/brain/awv067 2015
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B-Raf inhibitors induce epithelial differentiation in BRAF-mutant colorectal cancer cells. Herr R, Köhler M, Andrlová H, Weinberg F, Möller Y, Halbach S, Lutz L, Mastroianni J, Klose M, Bittermann N, Kowar S, Zeiser R, Olayioye MA, Lassmann S, Busch H, Boerries M, Brummer T. Cancer Res. 2015 Jan 1;75(1):216-29 10.1158/0008-5472.CAN-13-3686 2015
Cell segmentation and tracking in phase contrast images using graph cut with asymmetric boundary costs Robert Bensch, Olaf Ronneberger IEEE International Symposium on Biomedical Imaging (ISBI), 2015 2015
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Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells Funk, M.C., Bera, A.N., Menchen, T., Kuales, G., Thriene, K., Lienkamp, S.S., Dengjel, J., Omran, H., Frank, M., and Arnold, S.J. EMBO J. 2015 Apr 15;34(8):1078-89 10.15252/embj.201490805 2015
Differential retrotranslocation of mitochondrial Bax and Bak. Todt F, Cakir Z, Reichenbach F, Emschermann F, Lauterwasser J, Kaiser A, Ichim G, Tait SW, Frank S, Langer HF, Edlich F EMBO J. 2015 Jan 2;34(1):67-80 10.15252/embj.201488806 2015
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Hantavirus infection with severe proteinuria and podocyte foot-process effacement. Boehlke C, Hartleben B, Huber TB, Hopfer H, Walz G, Neumann-Haefelin E. Am J Kidney Dis. 2014 Sep;64(3):452-6 10.1053/j.ajkd.2014.04.030 2015
Identification of a new genomic hot spot of evolutionary diversification of protein function. Winkelmann A, You X, Grünewald N, Häussler U, Krestel H, Haas CA, Schwarz G, Chen W, Meier J. PLoS One. 2015 May 8;10(5) 10.1371/journal.pone.0125413 2015
Mitochondrial Dynamics and the ER: The Plant Perspective. Mueller, S.J., R. Reski Front Cell Dev Biol. 2015 Dec 23;3:78 10.3389/fcell.2015.00078 2015
Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains. Beck-García K, Beck-García E, Bohler S, Zorzin C, Sezgin E, Levental I, Alarcón B, Schamel WW Biochim Biophys Acta. 2015 Apr;1853(4):802-9 10.1016/j.bbamcr.2014.12.017 2015
Organizer-Derived WOX5 Signal Maintains Root Columella Stem Cells through Chromatin-Mediated Repression of CDF4 Expression. Pi, L., Aichinger, E., van der Graaff, E., Llavata-Peris, C., Weijers, D., Hennig, L., Groot, E., and Laux, T. Developmental Cell 33, 576-88. 10.1016/j.devcel.2015.04.024 2015
Stratified organization and disorganization of inner plexiform layer revealed by TNAP activity in healthy and diabetic rat retina. Kántor O, Varga A, Tóth R, Énzsöly A, Pálfi E, Kovács-Öller T, Nitschke R, Szél Á, Székely A, Völgyi B, Négyessy L, Somogyvári Z, Lukáts Á. Cell Tissue Res. 2015 Feb;359(2):409-421. 10.1007/s00441-014-2047-x 2015
Systematic analysis of how phytochrome B dimerization determines its specificity. Klose C, Venezia F, Hussong A, Kircher S, Schäfer E, Fleck C. Nat Plants. 2015 Jul 6;1:15090 10.1038/nplants.2015.90 2015
The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells. Yasunaga T, Hoff S, Schell C, Helmstadter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Muller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, and Walz G. J Cell Biol. 2015 Dec 7;211(5):963-73 10.1083/jcb.201502043 2015
The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin. Epting D, Slanchev K, Boehlke C, Hoff S, Loges NT, Yasunaga T, Indorf L, Nestel S, Lienkamp SS, Omran H, Kuehn EW, Ronneberger O, Walz G, Kramer-Zucker A Development. 2015 Jan 1;142(1):174-84 10.1242/dev.112250 2015
TSC1 Activates TGF-ß-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition. Thien A, Prentzell MT, Holzwarth B, Kläsener K, Kuper I, Boehlke C, Sonntag AG, Ruf S, Maerz L, Nitschke R, Grellscheid SN, Reth M, Walz G, Baumeister R, Neumann-Haefelin E, Thedieck K. Dev Cell. 2015 Mar 9;32(5):617-30 10.1016/j.devcel.2015.01.026 2015
Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos. Jank, T., Eckerle, S., Steinemann, M., Trillhaase, C., Schimpl, M., Wiese, S., van, A. D. M., Driever, W. and Aktories, K. Nat Commun. 2015 Jul 20;6:7807. 10.1038/ncomms8807 2015
A chemical switch for controlling viral infectivity Hörner M, Kaufmann B, Cotugno G, Wiedtke E, Büning H, Grimm D, Weber W Chem Commun (Camb). 2014 Sep 14;50(71):10319 10.1039/c4cc03292f 2014
Accurate Detection in Volumetric Images using Elastic Registration based Validation D. Mai, J. Dürr, K. Palme, O. Ronneberger German Conference on Pattern Recognition (GCPR): 453--463, 2014 10.1007/978-3-319-11752-2_37 2014
Caenorhabditis elegans OSM-11 signaling regulates SKN-1/Nrf during embryonic development and adult longevity and stress response. Dresen A, Finkbeiner S, Dottermusch M, Beume JS, Li Y, Walz G, Neumann-Haefelin E Dev Biol. 2015 Jan 29. pii: S0012-1606(15)00041-X. 10.1016/j.ydbio.2015.01.021 2014
Changes in neural network homeostasis trigger neuropsychiatric symptoms. Winkelmann A, Maggio N, Eller J, Caliskan G, Semtner M, Häussler U, Jüttner R, Dugladze T, Smolinsky B, Kowalczyk S, Chronowska E, Schwarz G, Rathjen FG, Rechavi G, Haas CA, Kulik A, Gloveli T, Heinemann U, Meier JC. J Clin Invest. 2014 Feb;124(2):696-711. 10.1172/JCI71472 2014
Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly Taschner M, Kotsis F, Braeuer P, Kuehn EW, Lorentzen E. J Cell Biol. 2014 Oct 27;207(2):269-82. 10.1083/jcb.201408002 2014
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Expression pattern and first functional characterization of riok-1 in Caenorhabditis elegans. Weinberg F, Schulze E, Fatouros C, Schmidt E, Baumeister R, Brummer T. Gene Expr Patterns. 2014 Jul;15(2):124-34na.2014.00145 10.1016/j.gep.2014.05.005 2014
Extensive postzygotic mosaicism for a novel keratin 10 mutation in epidermolytic ichthyosis. Kiritsi D, Nanda A, Kohlhase J, Bernhard C, Bruckner-Tuderman L, Happle R, Has C. Acta Derm Venereol. 2014 May;94(3):346-8. 10.2340/00015555-1695 2014
Functional architecture of an optic flow-responsive area that drives horizontal eye movements in zebrafish. Kubo F, Hablitzel B, Dal MM, Driever W, Baier H, Arrenberg AB Neuron 81: 1344-59. 10.1016/j.neuron.2014.02.043 2014
Improving Detection of Deformable Objects in Volumetric Data D. Mai, J. Dürr, K. Palme, O. Ronneberger British Machine Vision Conference (BMVC), 2014 10.5244/C.28.77 2014
Interaction with the Bardet-Biedl gene product TRIM32/BBS11 modifies the half-life and localization of Glis2/NPHP7. Ramachandran H, Schäfer T, Kim Y, Herfurth K, Hoff S, Lienkamp SS, Kramer-Zucker A, Walz G J Biol Chem. 2014 Mar 21;289(12):8390-401. 10.1074/jbc.M113.534024 2014
Molecular Heterogeneity of Epidermolysis Bullosa Simplex: Contribution of EXPH5 Mutations. Pigors M, Schwieger-Briel A, Leppert J, Kiritsi D, Kohlhase J,Bruckner-Tuderman L, Has C. J Invest Dermatol. 2014 Mar;134(3):842-5. 10.1038/jid.2013.373 2014
N-glycosylation determines the abundance of the transient receptor potential channel TRPP2. Hofherr A, Wagner C, Fedeles S, Somlo S, Köttgen M. J Biol Chem. 2014 May 23;289(21):14854-67. 10.1074/jbc.M114.562264 2014
nkx2.1 and nkx2.4 genes function partially redundant during development of the zebrafish hypothalamus, preoptic region, and pallidum. Manoli M, Driever W. Front Neuroanat. 2014 Dec 2;8:145 10.3389/fnana.2014.00145 2014
Optical Flow Guided Cell Segmentation and Tracking in Developing Tissue K. Liu, S. Lienkamp, A. Shindo, J. Wallingford, G. Walz, O. Ronneberger IEEE International Symposium on Biomedical Imaging (ISBI): 298--301, 2014 10.1109/ISBI.2014.6867868 2014
P2X7-dependent, but differentially regulated release of IL-6, CCL2, and TNF-a in cultured mouse microglia. Shieh CH, Heinrich A, Serchov T, van Calker D, Biber K Glia. 2014 Apr;62(4):592-607. 10.1002/glia.22628 2014
Pou5f1 protein expression and posttranslational modification during early zebrafish development. Lippok B, Song S, Driever W. Dev Dyn 243: 468-77. 10.1002/dvdy.24079 2014
Pou5f1/Oct4 promotes cell survival via direct activation of mych expression during zebrafish gastrulation. Kotkamp K, Kur E, Wendik B, Polok BK, Ben-Dor S, Onichtchouk D, et al. PLoS One 9: e92356. 10.1371/journal.pone.0092356 2014
Quantitative analysis of the mitochondrial and plastid proteomes of the moss Physcomitrella patens reveals protein macrocompartmentation and microcompartmentation. Mueller, S.J., D. Lang, S.N.W. Hoernstein, E.G.E. Lang, C. Schuessele, A. Schmidt, M. Fluck, D. Leisibach, C. Niegl, A.D. Zimmer, A. Schlosser, R. Reski Plant Physiol. 2014 Apr;164(4):2081-95 10.1104/pp.114.235754 2014
RhoA activation by CNFy restores cell-cell adhesion in kindlin-2 deficient keratinocytes. He Y, Sonnenwald T, Sprenger A, Hansen U, Dengjel J, Bruckner-Tuderman L, Schmidt G, Has C. J Pathol. 2014 Jul;233(3):269-80. 10.1002/path.4350 2014
Rotation-Invariant HOG Descriptors using Fourier Analysis in Polar and Spherical Coordinates K. Liu, H. Skibbe, T. Schmid, T. Blein, K. Palme, T. Brox, and O. Ronneberger Int J Computer Vision February 2014, Volume 106, Issue 3, pp 342-364 10.1007/s11263-013-0634-z 2014
Signaling Switch of the Axon Guidance Receptor Robo3 during Vertebrate Evolution. Zelina P, Blockus H, Zagar Y, Peres A, Friocourt F, Wu Z, Rama N, Fouquet C, Hohenester E, Tessier-Lavigne M, Schweitzer J, Roest Crollius H, Chedotal A Neuron. 2014 Dec 17;84(6):1258-72. 10.1016/j.neuron.2014.11.004 2014
Stochastic nanoroughness modulates neuron-astrocyte interactions and function via mechanosensing cation channels. Blumenthal NR, Hermanson O, Heimrich B, Shastri VP. Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16124-9. 10.1073/pnas.1412740111 2014
The iRoCS Toolbox--3D analysis of the plant root apical meristem at cellular resolution. Schmidt T, Pasternak T, Aubry D, Dovzhenko A, Teale W, Burkhardt H, Ronneberger O, Palme K. Plant J. 2014 Mar;77(5):806-14 10.1111/tpj.12429 2014
The irre Cell Recognition Module (IRM) Protein Kirre Is Required to Form the Reciprocal Synaptic Network of L4 Neurons in the Drosophila Lamina. Kevin Lüthy, Birgit Ahrens, Shilpa Rawal, Zhiyuan Lu, Dorota Tarnogorska, Ian A Meinertzhagen, Karl-Friedrich Fischbach J Neurogenet. 2014 Sep-Dec;28(3-4):291-301. 10.3109/01677063.2014.883390 2014
The Missense Mutation p.R1303Q in Type XVII Collagen Underlies Junctional Epidermolysis Bullosa Resembling Kindler Syndrome. Has C, Kiritsi D, Mellerio JE, Franzke CW, Wedgeworth E, Tantcheva-Poor I, Kernland-Lang K, Itin P, Simpson MA, Dopping-Hepenstal PJ, Fujimoto W, McGrath JA, Bruckner-Tuderman L. J Invest Dermatol. 2014 Mar;134(3):845-9. 10.1038/jid.2013.367 2014
TNAP activity is localized at critical sites of retinal neurotransmission across various vertebrate species. Kántor O, Varga A, Kovács-Öller T, Énzsöly A, Balogh L, Baksa G, Szepessy Z, Fonta C, Roe AW, Nitschke R, Szél Á, Négyessy L, Völgyi B, Lukáts Á. Cell Tissue Res. 2014 Oct;358(1):85-98. 10.1007/s00441-014-1944-3 2014
Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling. Löffek S, Hurskainen T, Jackow J, Sigloch FC, Schilling O, Tasanen K, Bruckner-Tuderman L, Franzke CW. PLoS One. 2014 Feb 5;9(2):e87263. 10.1371/journal.pone.0087263 2014
Validation of Micro-CT/FMT Multimodal in vivo Imaging in Rat D. Vonwill, J. Chistensen, S. Fischer, O. Ronneberger, and V.P. Shastri Mol Imaging Biol. 2014 Jun;16(3):350-61 10.1007/s11307-013-0698-8 2014
Novel and recurrent /AAGAB/ mutations: clinical variability and molecular consequences. Kiritsi D, Chmel N, Arnold AW, Jakob T, Bruckner-Tuderman L, Has C. J Invest Dermatol. 2013 Oct;133(10):2483-6. 10.1038/jid.2013.171 2013
vglut2 and gad expression reveal distinct patterns of dual GABAergic versus glutamatergic cotransmitter phenotypes of dopaminergic and noradrenergic neurons in the zebrafish brain. Filippi A, Mueller T, Driever W. J Comp Neurol 522: 2019-37. 10.1002/cne.23524 2013
A complex of BBS1 and NPHP7 is required for cilia motility in zebrafish. Kim YH, Epting D, Slanchev K, Engel C, Walz G, Kramer-Zucker A PLoS One. 2013 Sep 12;8(9):e72549 10.1371/journal.pone.0072549 2013
A mutation in cnot8, component of the Ccr4-not complex regulating transcript stability, affects expression levels of developmental regulators and reveals a role of Fgf3 in development of caudal hypothalamic dopaminergic neurons. Koch P, Lohr HB, Driever W PLoS One 9: e113829. 10.1371/journal.pone.0113829 2013
A novel domain regulating degradation of the glomerular slit diaphragm protein podocin in cell culture systems. Gödel M, Ostendorf BN, Baumer J, Weber K, Huber TB. PLoS One. 2013;8(2):e57078. 10.1371/journal.pone.0057078 2013
ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3 Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstädter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS Nat Genet. 2013 Aug;45(8):951-6. 10.1038/ng.2681 2013
aPKC?/? and aPKC? contribute to podocyte differentiation and glomerular maturation. Hartleben B, Widmeier E, Suhm M, Worthmann K, Schell C, Helmstädter M, Wiech T, Walz G, Leitges M, Schiffer M, Huber TB. J Am Soc Nephrol. 2013 Feb;24(2):253-67. 10.1681/ASN.2012060582 2013
Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK. Geissler, A., Haun, F., Frank, D., Wieland, K., Simon, M., Idzko, M., Davis, R., Maurer, U. & Borner, C. Cell Death Differ. (2013) 20, 1317–1329 10.1038/cdd.2013.78 2013
Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling. Schober A, Parlato R, Huber K, Kinscherf R, Hartleben B, Huber TB, Schütz G, Unsicker K. J Neuroendocrinol. 2013 Jan;25(1):34-47. 10.1111/j.1365-2826.2012.02367.x 2013
Collagen VII plays a dual role in wound healing. Nyström A, Velati D, Mittapalli VR, Fritsch A, Kern JS, Bruckner-Tuderman L. J Clin Invest. 2013 Aug;123(8):3498-509. 10.1172/JCI68127 2013
Discriminative Detection and Alignment in Volumetric Data Dominic Mai, Philipp Fischer, Thomas Blein, Jasmin Dürr, Klaus Palme, Thomas Brox, Olaf Ronneberger Pattern Recognition Lecture Notes in Computer Science Volume 8142, 2013, pp 205-214 10.1007/978-3-642-40602-7_21 2013
Enlightening the brain: linking deep brain photoreception with behavior and physiology. Fernandes AM, Fero K, Driever W, Burgess HA Bioessays 35: 775-9. 10.1002/bies.201300034 2013
Epidermolysis bullosa simplex ogna revisited. Kiritsi D, Pigors M, Tantcheva-Poor I, Wessel C, Arin MJ, Kohlhase J, Bruckner-Tuderman L, Has C. J Invest Dermatol. 2013 Jan;133(1):270-3. 10.1038/jid.2012.248 2013
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Ectodomain shedding generates Neoepitopes on collagen XVII, the major autoantigen for bullous pemphigoid. Nishie W, Lamer S, Schlosser A, Licarete E, Franzke CW, Hofmann SC, Jackow J, Sitaru C, Bruckner-Tuderman L. J Immunol. 2010 Oct 15;185(8):4938-47. 10.4049/jimmunol.1001524 2010
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Harmonic filters for 3D multichannel data: rotation invariant detection of mitoses in colorectal cancer. Schlachter M, Reisert M, Herz C, Schlürmann F, Lassmann S, Werner M, Burkhardt H, Ronneberger O. IEEE Trans Med Imaging. 2010 Aug;29(8):1485-95. 10.1109/tmi.2010.2049856 2010
Humic substances induce lateral root formation and expression of the early auxin-responsive IAA19 gene and DR5 synthetic element in Arabidopsis. Trevisan S, Pizzeghello D, Ruperti B, Francioso O, Sassi A, Palme K, Quaggiotti S, Nardi S. Plant Biol (Stuttg). 2010 Jul 1;12(4):604-14. 10.1111/j.1438-8677.2009.00248.x 2010
Inhibition of mitochondrial fusion by a-synuclein is rescued by PINK1, Parkin and DJ-1. Kamp F, Exner N, Lutz AK, Wender N, Hegermann J, Brunner B, Nuscher B, Bartels T, Giese A, Beyer K, Eimer S, Winklhofer KF, Haass C. EMBO J. 2010 Oct 20;29(20):3571-89. 10.1038/emboj.2010.223 2010
Intracellular FRET analysis of lipid/DNA complexes using flow cytometry and fluorescence imaging techniques Schneider S, Lenz D, Holzer M, Palme K, Süss R. J Control Release. 2010 Aug 3;145(3):289-96. 10.1016/j.jconrel.2010.04.016 2010
Inversin relays Frizzled-8 signals to promote proximal pronephros development. Lienkamp S, Ganner A, Boehlke C, Schmidt T, Arnold SJ, Schäfer T, Romaker D, Schuler J, Hoff S, Powelske C, Eifler A, Krönig C, Bullerkotte A, Nitschke R, Kuehn EW, Kim E, Burkhardt H, Brox T, Ronneberger O, Gloy J, Walz G. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20388-93. 10.1073/pnas.1013070107 2010
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MGOUN1 encodes an Arabidopsis type IB DNA topoisomerase required in stem cell regulation and to maintain developmentally regulated gene silencing. Graf P, Dolzblasz A, Würschum T, Lenhard M, Pfreundt U, Laux T. Plant Cell. 2010 Mar;22(3):716-28. 10.1105/tpc.109.068296 2010
Modelling polar auxin transport in developmental patterning. Santos F, Teale W, Fleck C, Volpers M, Ruperti B, Palme K. Plant Biol (Stuttg). 2010 Sep;12 Suppl 1:3-14. 10.1111/j.1438-8677.2010.00388.x 2010
Naked dense bodies provoke depression. Hallermann S, Kittel RJ, Wichmann C, Weyhersmüller A, Fouquet W, Mertel S, Owald D, Eimer S, Depner H, Schwärzel M, Sigrist SJ, Heckmann M. J Neurosci. 2010 Oct 27;30(43):14340-5. 10.1523/jneurosci.2495-10.2010 2010
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Preferential adhesion maintains separation of ommatidia in the Drosophila eye. Bao S, Fischbach KF, Corbin V, Cagan RL. Dev Biol. 2010 Aug 15;344(2):948-56. 10.1016/j.ydbio.2010.06.013 2010
Primary cilia regulate mTORC1 activity and cell size through Lkb1. Boehlke C, Kotsis F, Patel V, Braeg S, Voelker H, Bredt S, Beyer T, Janusch H, Hamann C, Gödel M, Müller K, Herbst M, Hornung M, Doerken M, Köttgen M, Nitschke R, Igarashi P, Walz G, Kuehn EW. Nat Cell Biol. 2010 Nov;12(11):1115-22 10.1038/ncb2117 2010
PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation. Gao H, Wang Y, Wegierski T, Skouloudaki K, Pütz M, Fu X, Engel C, Boehlke C, Peng H, Kuehn EW, Kim E, Kramer-Zucker A, Walz G. Hum Mol Genet. 2010 Jan 1;19(1):16-24. 10.1093/hmg/ddp463 2010
Proper layering is important for precisely timed activation of hippocampal mossy cells. Kowalski J, Geuting M, Paul S, Dieni S, Laurens J, Zhao S, Drakew A, Haas CA, Frotscher M, Vida I. Cereb Cortex. 2010 Sep;20(9):2043-54. 10.1093/cercor/bhp267 2010
Recognition of pre- and postsynaptic neurons via nephrin/NEPH1 homologs is a basis for the formation of the Drosophila retinotopic map. Sugie A, Umetsu D, Yasugi T, Fischbach KF, Tabata T. Development. 2010 Oct;137(19):3303-13. 10.1242/dev.047332 2010
Regulation of Frizzled-dependent planar polarity signaling by a V-ATPase subunit. Hermle T, Saltukoglu D, Grünewald J, Walz G, Simons M. Curr Biol. 2010 Jul 27;20(14):1269-76. 10.1016/j.cub.2010.05.057 2010
Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L). Lindenboim L, Blacher E, Borner C, Stein R. Cell Death Differ. 2010 Feb;17(2):346-59. 10.1038/cdd.2009.145 2010
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Seasonal and cell type specific expression of sulfate transporters in the phloem of Populus reveals tree specific characteristics for SO(4)(2-) storage and mobilization. Dürr J, Bücking H, Mult S, Wildhagen H, Palme K, Rennenberg H, Ditengou F, Herschbach C. Plant Mol Biol. 2010 Mar;72(4-5):499-517. 10.1007/s11103-009-9587-6 2010
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Targeted knock-out of a gene encoding sulfite reductase in the moss Physcomitrella patens affects gametophytic and sporophytic development. Wiedemann G, Hermsen C, Melzer M, Büttner-Mainik A, Rennenberg H, Reski R, Kopriva S. FEBS Lett. 2010 Jun 3;584(11):2271-8. 10.1016/j.febslet.2010.03.034 2010
The polycotyledon (pct1-2) mutant of tomato shows enhanced accumulation of PIN1 auxin transport facilitator protein. Kharshiing EV, Kumar GP, Ditengou FA, Li X, Palme K, Sharma R. Plant Biol (Stuttg). 2010 Jan;12(1):224-8. 10.1111/j.1438-8677.2009.00267.x 2010
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